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品种反应性 主要应用 宿主 格式 抗体类型 H ICC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABC349 描述 Anti-ABCA7 Antibody Alternate Names - ABCA7
- ATP-binding Cassette Sub-family A (ABC1) member 7
- ABC1
- ABC Transporter 1
- ATP-binding Cassette 1
- ATP-binding Cassette Transporter 1
- CERP
- ABCA-SSN
- Autoantigen SS-N
- Macrophage ABC transporter
背景信息 ATP-binding cassette sub-family A member 7 (ABCA7), also known as ABCA-SSN and Macrophage ABC transporter, is a full-size ABC transporter consisting of two sets of the multiple membrane-spanning domains plus the Walker motifs for the ATP interaction. It uses ATP hydrolysis to catalyze the transport of various molecules across cell membranes. ABCA7 is involved in phagocytosis by macrophages of apoptotic cells, binds to APOA1, may function in phospholipid and cholesterol efflux from cells, and may regulate cellular ceramide homeostasis during keratinocyte differentiation The high ABCA7 expression levels in peripheral leukocytes, thymus, spleen and bone marrow indicates a role in the immune system lipid homeostasis. ABCA1 is also highly expressed in fetal tissues, especially the liver. 产品信息 格式 Affinity Purified 控制 - HEK293 cell lysate
演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. 应用 应用 Anti-ABCA7 Antibody is a highly specific rabbit polyclonal antibody, that targets ABCA7 & has been tested in western blotting & ICC. 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 Immunocytochemistry Analysis: 5 µg/mL from a representative lot detected ABCA7 in HEK293 cells. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human ABCA7. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody 基因符号 - ABCA7
纯化方法 Antigen Affinity purified UniProt编号 - Q8IZY2
产品使用声明 质量保证 Evaluated by Western Blotting in HEK293 cell lysate.
Western Blotting Analysis: 1µg/mL of this antibody detected ABCA7 in 15 µg of HEK293 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,MAB343,Anti-APP Antibody, APP 643-695 CT fragment, clone 2.F2.19B4
下一件merck millipore产品：merck millipore,默克密理博,07-807,Anti-phospho-Met (Tyr1003) Antibody
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