merck millipore,默克密理愽
  • merck millipore,默克密理博,227013,CCR4 Antagonist - CAS 864289-85-0 - Calbiochem

  • merck millipore,默克密理博,227013,CCR4 Antagonist - CAS 864289-85-0 - Calbiochem

    产品名称：CCR4 Antagonist - CAS 864289-85-0 - Calbiochem
    产品型号：227013
    The CCR4 Antagonist, also referenced under CAS 864289-85-0, controls the biological activity of CCR4. This small molecule/inhibitor is primarily used for Membrane applications.

    merck millipore,默克密理博,227013,CCR4 Antagonist - CAS 864289-85-0 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,227013,CCR4 Antagonist - CAS 864289-85-0 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₇H₄₁N₅O₂ • 0.5 H₂O864289-85-0
    描述
    概述 A cell-permeable diaminoquinazoline compound that acts as a potent antagonist against the G-protein-coupled chemokine receptor CCR4 (IC50 = 73 and 18 nM against CCL22-binding and CCL22-induced GTPγS recruitment, respectively). Shown to inhibit CCL22/CCR4-mediated chemotaxis in both murine and human cultures (IC50 = 39 and 140 nM, respectively).
    产品目录编号 227013
    品牌系列 Calbiochem®
    同义词 2-(1,4ʹ-Bipiperidine-1ʹ-yl)-N-cycloheptyl-6,7-dimethoxyquinazolin-4-amine, C-021
    参考
    参考 Yokoyama, K., et al. 2008. Bioorg. Med. Chem. 16, 7021.
    产品信息
    CAS号 864289-85-0
    形式 Light beige solid
    Hill配方 C₂₇H₄₁N₅O₂ • 0.5 H₂O
    化学配方 C₂₇H₄₁N₅O₂ • 0.5 H₂O
    Molar Mass 476.7
    结构配方图像
    生物信息
    纯度 ≥97% by HPLC
    理化信息
    溶解度 DMSO or EtOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,227013,CCR4 Antagonist - CAS 864289-85-0 - Calbiochem

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