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merck millipore,默克密理博,516485,Pepstatin A Methyl Ester - Calbiochem
产品名称：Pepstatin A Methyl Ester - Calbiochem
产品型号：516485
A cell-permeable methyl ester derivative of Pepstatin A that acts as a potent, non-competitive, transition-state analog inhibitor of γ-secretase.
merck millipore,默克密理博,516485,Pepstatin A Methyl Ester - Calbiochem
- 产品介绍
重要规格表
经验配方 C₃₅H₆₅N₅O₉ 描述 概述 A cell-permeable methyl ester derivative of Pepstatin A (Cat. No. 516481) that acts as a potent, non-competitive, transition-state analog inhibitor of γ-secretase (Kis = 150 nM, Kii = 320 nM in solubilized human γ-secretase at 20°C; Kis is the inhibition constant for inhibitor binding to the free enzyme and Kii is the inhibition constant for inhibitor binding to the Enzyme-Substrate complex). Sta = (3S,4S)-4-Amino-3-hydroxy-6-methyl-heptanoic acid. 产品目录编号 516485 品牌系列 Calbiochem®
同义词 Isovaleryl-V V-Sta-A-Sta-OCH₃, PME 参考 参考 Tian, G., et al. 2002. J. Biol. Chem. 277, 31499.
Zhang, L., et al. 2001. Biochemistry 40, 5049.
Murphy, M.P., et al. 1999. J. Biol. Chem. 274, 11914.产品信息 具有ATP竞争性 N 形式 Lyophilized Hill配方 C₃₅H₆₅N₅O₉ 化学配方 C₃₅H₆₅N₅O₉ Molar Mass 699.9 可逆 N 结构配方图像 生物信息 主靶 γ-secretase 纯度 ≥95% by HPLC 理化信息 细胞可渗透 Y 溶解度 DMSO 储存和货运信息 货运代码 Blue Ice Only
毒性 Standard Handling
储存 -20°C
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid freeze/thaw cycles of solutions. 包装信息 惰性气体下包装 Packaged under inert gas
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