merck millipore,默克密理愽
  • merck millipore,默克密理博,AB1876,Anti-Vascular Endothelial Growth Factor Antibody

  • merck millipore,默克密理博,AB1876,Anti-Vascular Endothelial Growth Factor Antibody

    产品名称：Anti-Vascular Endothelial Growth Factor Antibody
    产品型号：AB1876
    Anti-Vascular Endothelial Growth Factor Antibody is an antibody against Vascular Endothelial Growth Factor for use in ELISA & WB.

    merck millipore,默克密理博,AB1876,Anti-Vascular Endothelial Growth Factor Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB1876,Anti-Vascular Endothelial Growth Factor Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    MWB, ELISARbPurifiedPolyclonal Antibody
    描述
    产品目录编号 AB1876
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Vascular Endothelial Growth Factor Antibody
    Alternate Names
    • VEGF
    产品信息
    格式 Purified
    演示 Immunoglobulin purified by HPLC. Liquid (sterile filtered) with no preservatives.
    应用
    应用 Anti-Vascular Endothelial Growth Factor Antibody is an antibody against Vascular Endothelial Growth Factor for use in ELISA & WB.
    主要应用
    • Western Blotting
    • ELISA
    应用说明 Western blot: 1:100-1:1,000

    ELISA: 1:100-1:1,000

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 Recombinant mouse VEGF.
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Reacts with mouse VEGF. No cross-reactivity with WHO standards to an extensive panel of cytokines and growth factors by EIA.
    品种反应性 Mouse
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_003376.4
    • NM_001025366.1
    • NM_001025367.1
    • NM_001025368.1
    • NM_001025369.1
    • NM_001025370.1
    • NM_001033756.1
    Entrez基因汇总 This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.
    基因符号
    • VEGF
    • VEGFA
    • VPF
    • VEGF-A
    • MGC70609
    UniProt编号
    • P15692
    UniProt汇总 FUNCTION: SwissProt: P15692 # Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis, and induces permeabilization of blood vessels. Binds to the VEGFR1/Flt-1 and VEGFR2/Kdr receptors, heparan sulfate and heparin. Neuropilin-1 binds isoforms VEGF-165 and VEGF-145.
    SIZE: 232 amino acids; 27042 Da
    SUBUNIT: Homodimer; disulfide-linked. Also found as heterodimer with PlGF (By similarity).
    SUBCELLULAR LOCATION: Secreted. Note=VEGF121 is acidic and freely secreted. VEGF165 is more basic, has heparin-binding properties and, although a signicant proportion remains cell-associated, most is freely secreted. VEGF189 is very basic, it is cell-associated after secretion and is bound avidly by heparin and the extracellular matrix, although it may be released as a soluble form by heparin, heparinase or plasmin.
    TISSUE SPECIFICITY: The VEGF189, VEGF-165 and VEGF-121 isoforms are widely expressed, whereas the VEGF206 and VEGF-145 are uncommon.
    SIMILARITY: SwissProt: P15692 ## Belongs to the PDGF/VEGF growth factor family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at 2-8°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,AB1876,Anti-Vascular Endothelial Growth Factor Antibody

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