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merck millipore,默克密理博,565777,γ-Secretase Inhibitor XVI - CAS 208255-51-0 - Calbiochem
产品名称:γ-Secretase Inhibitor XVI - CAS 208255-51-0 - Calbiochem
产品型号:565777
The γ-Secretase Inhibitor XVI, also referenced under CAS 208255-51-0, controls the biological activity of γ-Secretase. This small molecule/inhibitor is primarily used for Neuroscience applications.
merck millipore,默克密理博,565777,γ-Secretase Inhibitor XVI - CAS 208255-51-0 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₂₀H₂₀F₂N₂O₄ 208255-51-0 描述 概述 A cell-permeable γ-secretase inhibitor (IC50 Aβ = ~10 nM in 7PA2 cells) with anti-aggregation properties. Prevents early Aβ oligomerization by selectively blocking the Aβ dimer and trimer formation. 产品目录编号 565777 品牌系列 Calbiochem®
同义词 DAPM, N-[N-3,5-Difluorophenacetyl]-L-alanyl-S-phenylglycine Methyl Ester 参考 参考 Walsh, D.M., et al. 2002. Nature 416, 535. 产品信息 CAS号 208255-51-0 具有ATP竞争性 N 形式 White solid Hill配方 C₂₀H₂₀F₂N₂O₄ 化学配方 C₂₀H₂₀F₂N₂O₄ Molar Mass 390.4 可逆 N 结构配方图像 生物信息 主靶 γ-secretase Aβ₄₀ in 7PA2 cells 主靶IC50 10 nM 纯度 ≥97% by HPLC 理化信息 细胞可渗透 Y 溶解度 DMSO 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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