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描述 概述 Recombinant, human androgen receptor (AR) fused at the N-terminus to a Flag-Tag™ sequence and at the C-terminus to His•Tag® sequence, expressed in S. frugiperda insect cells expressed using a baculovirus expression system, and purified by affinity chromatography. The activity of androgen is mediated by the binding of the intracellular androgen receptor which, when activated, translocates to the nucleus and modulates specific gene transcription by interaction with cis-acting hormone response elements in the target genes. 产品目录编号 346101 品牌系列 Calbiochem®
同义词 AR, Human, Recombinant, Dihydrotestosterone Receptor, Human, Recombinant 参考 参考 Chen, G., et al. 2005. Prostate 63, 395.
Estebanez-Perpina, E., et al. 2005, J. Biol. Chem. 280, 8060.
Gao, S., et al. 2005. Mol. Endocrinol. 19, 1792.
Hillmer, A.M., et al. 2005. Am. J. Hum. Genet. 77, 140.
Kinoshita, M., et al. 2005, Int. J. Urol. 12, 390.
Lim, J.T., et al. 2005. Proc. Natl. Acad. Sci. U.S.A. 102, 5156;
Marques, R.B., et al. 2005. Int. J. Cancer 117, 221;
Metzger, E., et al. 2005. Nature 437, 436;
Murthy, S., et al. 2005. Prostate 64, 362;
Chang, C., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 5946.产品信息 活性 1.0 unit is equivalent to 1 ng protein. 20 units are sufficient for a gel-mobility shift assay and 100 units are sufficient for a protein-protein interaction assay. 形式 Liquid 配方 In 100 mM KCl, 20 mM Tris-HCl, 1 mM DTT, 200 µM EDTA, 20% glycerol, pH 8.0. Molar Mass 101000 生物信息 浓缩标签 Please refer to vial label for lot-specific concentration
储存和货运信息 货运代码 Dry Ice Only
毒性 Standard Handling
储存 ≤ -70°C
无需冷冻 No
特殊指南 Following initial thaw, aliquot and freeze (-70°C).
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