merck millipore,默克密理博,554720,trans-Retinoic Acid - CAS 302-79-4

搜索"Merck Millipore 密理愽"产品

Merck Millipore 默克密理愽

当前位置：首页 > >Merck Millipore > 生命科学研究
生命科学研究

merck millipore,默克密理博,554720,trans-Retinoic Acid - CAS 302-79-4 - Calbiochem
产品名称：trans-Retinoic Acid - CAS 302-79-4 - Calbiochem
产品型号：554720
Potent modulator of growth and differentiation. Inhibits melanocyte adhesion, motility, and growth.

merck millipore,默克密理博,554720,trans-Retinoic Acid - CAS 302-79-4 - Calbiochem

产品介绍

merck millipore,默克密理博,554720,trans-Retinoic Acid - CAS 302-79-4 - Calbiochem

重要规格表

经验配方	CAS号
C₂₀H₂₈O₂	302-79-4

描述
概述	Potent modulator of growth and differentiation. Exerts its effects by binding to nuclear retinoic acid receptors (RARs) which directly regulate gene expression. Inhibits melanocyte adhesion, motility, and growth. Has keratolytic activity. Induces differentiation of tumor cells of neural origin. Induces apoptosis in acute promyelocytic carcinoma cells. PROTECT FROM AIR.
产品目录编号	554720
品牌系列	Calbiochem®
同义词	Tretinoin, ATRA, Vitamin A Acid

参考
参考	Tosi, P., et al. 1994. Leuk. Lymphoma 14, 503. Clagett-Dame, M., et al. 1993. Arch. Biochem. Biophys. 300, 684. Labbaye, C., et al. 1993. Blood 81, 475. Sakashita, A., et al. 1993. Blood 81, 1009. Situ, R., et al. 1993. Dermatology 186, 38. Tini, M., et al. 1993. Genes Develop. 7, 295. Leid, M., et al. 1992. Trends Biochem. Sci. 17, 427. Sharpe, C.R. 1991. Neuron 7, 239. Thaller, C. and Eichele, G. 1990. Nature 345, 815.

参考

Tosi, P., et al. 1994. Leuk. Lymphoma 14, 503.
Clagett-Dame, M., et al. 1993. Arch. Biochem. Biophys. 300, 684.
Labbaye, C., et al. 1993. Blood 81, 475.
Sakashita, A., et al. 1993. Blood 81, 1009.
Situ, R., et al. 1993. Dermatology 186, 38.
Tini, M., et al. 1993. Genes Develop. 7, 295.
Leid, M., et al. 1992. Trends Biochem. Sci. 17, 427.
Sharpe, C.R. 1991. Neuron 7, 239.
Thaller, C. and Eichele, G. 1990. Nature 345, 815.

产品信息
CAS号	302-79-4
形式	Yellow solid
Hill配方	C₂₀H₂₈O₂
化学配方	C₂₀H₂₈O₂
Molar Mass	300.4
吸湿	Hygroscopic
结构配方图像

生物信息
纯度	≥95% by assay

理化信息
溶解度	DMSO

GHS安全信息
RTECS	VH6475000

安全信息
R相	R: 22-36/37/38-63 Harmful if swallowed. Irritating to eyes, respiratory system and skin. Possible risk of harm to the unborn child.
S相	S: 22-26-36 Do not breathe dust. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing.

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Harmful & Carcinogenic / Teratogenic
储存	+2°C to +8°C
避光	Protect from light
吸湿	Hygroscopic
无需冷冻	No
特殊指南	Following reconstitution, store in the refrigerator (4°C). DMSO stock solutions are stable for up to 2 weeks at 4°C.