merck millipore,默克密理愽
  • merck millipore,默克密理博,100050,1400W - CAS 214358-33-5 - Calbiochem

  • merck millipore,默克密理博,100050,1400W - CAS 214358-33-5 - Calbiochem

    产品名称：1400W - CAS 214358-33-5 - Calbiochem
    产品型号：100050
    A selective, cell-permeable, irreversible, slow, tight-binding inhibitor of inducible nitric oxide synthase (iNOS; Kd = 7 nM).

    merck millipore,默克密理博,100050,1400W - CAS 214358-33-5 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,100050,1400W - CAS 214358-33-5 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₀H₁₅N₃ · 2HCl214358-33-5
    描述
    概述 A selective, cell-permeable, irreversible, slow, tight-binding inhibitor of inducible nitric oxide synthase (iNOS; Kd = 7 nM). Suitable for use in both in vitro and in vivo systems. Has a protective effect against cerebral ischemia by reducing ischemic lesion volumes. Exhibits greater than 5000- and 200-fold potency against human iNOS relative to eNOS and nNOS, respectively, and greater than 1000-fold potency against rat iNOS relative to eNOS.
    产品目录编号 100050
    品牌系列 Calbiochem®
    同义词 N-(3-Aminomethyl)benzylacetamidine, 2HCl
    参考
    参考 Parmentier, S., et al. 1999. Br. J. Pharmacol. 127, 546.
    Cardenas, A., et al. 1998. Eur. J. Pharmacol. 354, 161.
    Parrino, P.E., et al. 1998. Ann. Thorac. Surg. 66, 733.
    Garvey, E.P., et al. 1997. J. Biol. Chem. 272, 4959.
    Laszlo, F., and Whittle, B.J. 1997. Eur. J. Pharmacol. 334, 99.
    Thomsen, L.L., et al. 1997. Cancer Res. 57, 3300.
    产品信息
    CAS号 214358-33-5
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₁₀H₁₅N₃ · 2HCl
    化学配方 C₁₀H₁₅N₃ · 2HCl
    Molar Mass 250.2
    吸湿 Hygroscopic
    可逆 N
    结构配方图像
    生物信息
    主靶 iNOS
    主靶IC50 Kd = 7 nM against inducible nitric oxide synthase (iNOS)
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 MeOH or H₂O
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,100050,1400W - CAS 214358-33-5 - Calbiochem

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