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merck millipore,默克密理博,553511,Rac1 Inhibitor II - CAS 1090893-12-1 - Calbiochem
产品名称：Rac1 Inhibitor II - CAS 1090893-12-1 - Calbiochem
产品型号：553511
The Rac1 Inhibitor II, also referenced under CAS 1090893-12-1, controls the biological activity of Rac1. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applica More>>
merck millipore,默克密理博,553511,Rac1 Inhibitor II - CAS 1090893-12-1 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₂₀H₂₁N₃O₅S 1090893-12-1 描述 概述 A cell-permeable isoxazolyl-benzamide compound that is more effective than NSC23766 (Cat. Nos. 553502 & 553508) in inhibiting PDGF-BB- (Cat. No. 521225) induced cellular Rac1 activation (45.8% vs 11.1% inhibition by 4 h pretreatment of the respective compound at 50 µM) in serum-starved SMCs (human aortic smooth muscle cells) by interfering Rac1-Tiam1 interaction, while exhibiting no effect toward cellular Cdc42 and RhoA activation or Rac1 interaction to its effector Pak1. Shown to effectively prevent PDGF-BB-induced membrane ruffling and lamellipodia formation in serum-starved 3T3 cells (4 h pretreatment at 25 µM). Also available in InSolution™ format (Cat. No. 553512). 产品目录编号 553511 品牌系列 Calbiochem®
同义词 3-((3,5-Dimethylisoxazol-4-yl)methoxy)-N-(4-methyl-3-sulfamoyl-phenyl)benzamide, Z62954982 参考 参考 Ferri, N., et al. 2009. J. Med. Chem. 52, 4087. 产品信息 CAS号 1090893-12-1 形式 Off-white solid Hill配方 C₂₀H₂₁N₃O₅S 化学配方 C₂₀H₂₁N₃O₅S Molar Mass 415.5 生物信息 纯度 ≥93% by HPLC 理化信息 溶解度 DMSO 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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