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  • merck millipore,默克密理博,AB3516P,Anti-Sodium-Calcium Exchanger 1 Antibody

  • merck millipore,默克密理博,AB3516P,Anti-Sodium-Calcium Exchanger 1 Antibody

    产品名称：Anti-Sodium-Calcium Exchanger 1 Antibody
    产品型号：AB3516P
    Anti-Sodium-Calcium Exchanger 1 Antibody is an antibody against Sodium-Calcium Exchanger 1 for use in ELISA & WB.

    merck millipore,默克密理博,AB3516P,Anti-Sodium-Calcium Exchanger 1 Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB3516P,Anti-Sodium-Calcium Exchanger 1 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    RWB, ELISARbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB3516P
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Sodium-Calcium Exchanger 1 Antibody
    Alternate Names
    • NCX1
    产品信息
    格式 Affinity Purified
    演示 Affinity purified immunoglobulin. Liquid in PBS containing 0.1% BSA.
    应用
    应用 Anti-Sodium-Calcium Exchanger 1 Antibody is an antibody against Sodium-Calcium Exchanger 1 for use in ELISA & WB.
    主要应用
    • Western Blotting
    • ELISA
    应用说明 Western blot: 1-10 μg/mL using ECL.





    ELISA: 0.5-1 μg/mL using 1 μg/mL control peptide per well.

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 A 23 amino acid peptide sequence within the cytoplasmic domain 3 rat NCX1 (Low et al. 1993; Furman et al. 1993; Lee et al. 1994; Nicoll et al. 1996; Kumoro et al. 1992; Blaustein & Lederer 1999).
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Recognizes rat Sodium Calcium Exchanger 1 (NCX1). The immunogen shows no significant sequence homology with other NCX proteins.
    品种反应性 Rat
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_021097.2
    Entrez基因汇总 In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.[supplied by OMIM]
    基因符号
    • MGC119581
    • SLC8A1
    • NCX1
    • DKFZp779F0871
    • +Ca
    • CNC
    • Na
    UniProt编号
    • P32418
    UniProt汇总 FUNCTION: SwissProt: P32418 # Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores.
    SIZE: 973 amino acids; 108547 Da
    SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
    TISSUE SPECIFICITY: Cardiac sarcolemma.
    SIMILARITY: SwissProt: P32418 ## Belongs to the sodium/potassium/calcium exchanger family. SLC8 subfamily. & Contains 2 Calx-beta domains.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 50 µg

    merck millipore,默克密理博,AB3516P,Anti-Sodium-Calcium Exchanger 1 Antibody

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