• merck millipore,默克密理博,324732,ErbB2 Inhibitor II - CAS 928207-02-7 - Calbiochem
  • merck millipore,默克密理博,324732,ErbB2 Inhibitor II - CAS 928207-02-7 - Calbiochem

    产品名称:ErbB2 Inhibitor II - CAS 928207-02-7 - Calbiochem
    产品型号:324732
    The ErbB2 Inhibitor II, also referenced under CAS 928207-02-7, controls the biological activity of ErbB2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applic More>>

    merck millipore,默克密理博,324732,ErbB2 Inhibitor II - CAS 928207-02-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,324732,ErbB2 Inhibitor II - CAS 928207-02-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₅H₁₀N₄O928207-02-7
    描述
    概述 A cell-permeable triazole compound that targets the ATP-binding site of erbB2/HER2 and reduces the phosphorylation of erbB2 in MDA-MB-453 cells (IC50 = 6.6 µM), but not that of the overexpressed erbB1 in MDA-MB-468 cells even at concentrations as high as 100 µM. Shown to suppress MDA-MB-453 growth with an IC50 of 30.9 µM.
    产品目录编号 324732
    品牌系列 Calbiochem®
    同义词 4-(3-Phenoxyphenyl)-5-cyano-2H-1,2,3-triazole
    参考
    参考 Cheng, Z. Y., et al. 2007. Bioorg. Med. Chem. 15, 1533.
    产品信息
    CAS号 928207-02-7
    形式 Yellow solid
    Hill配方 C₁₅H₁₀N₄O
    化学配方 C₁₅H₁₀N₄O
    Molar Mass 262.3
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO
    安全信息
    R相 R: 36/37/38

    Irritating to eyes, respiratory system and skin.
    S相 S: 26-36-45

    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    Wear suitable protective clothing.
    In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Irritant
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,324732,ErbB2 Inhibitor II - CAS 928207-02-7 - Calbiochem

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