merck millipore,默克密理愽
  • merck millipore,默克密理博,506153,p38 MAP Kinase Inhibitor IV - CAS 1638-41-1 - Calbiochem

  • merck millipore,默克密理博,506153,p38 MAP Kinase Inhibitor IV - CAS 1638-41-1 - Calbiochem

    产品名称：p38 MAP Kinase Inhibitor IV - CAS 1638-41-1 - Calbiochem
    产品型号：506153
    The p38 MAP Kinase Inhibitor IV, also referenced under CAS 1638-41-1, controls the biological activity of p38 MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosph More>>

    merck millipore,默克密理博,506153,p38 MAP Kinase Inhibitor IV - CAS 1638-41-1 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,506153,p38 MAP Kinase Inhibitor IV - CAS 1638-41-1 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₂H₄Cl₆O₄S1638-41-1
    描述
    概述 A cell-permeable symmetrical sulfone compound that acts as a potent and ATP-competitive inhibitor of p38α/β MAPK (IC50 = 130 and 550 nM, respectively), while exihibiting much reduced activity (≤23% inhibition at 1 µM) against p38γ/δ, ERK1/2, and JNK1/2/3. Shown to be more effective than SB 203850 (Cat. Nos. 559389, 559395, and 559398) in inhibiting LPS-induced IL-1β release from hPBMC (100% vs. 50% inhibition with 100 µM respective inhibitor).
    产品目录编号 506153
    品牌系列 Calbiochem®
    同义词 2,2ʹ-Sulfonyl-bis-(3,4,6-trichlorophenol), MT4
    参考
    参考 Liu, Y.C., et al. 2007. Biochem. Biophys. Res. Commun. 352, 656.
    产品信息
    CAS号 1638-41-1
    形式 Light yellow solid
    Hill配方 C₁₂H₄Cl₆O₄S
    化学配方 C₁₂H₄Cl₆O₄S
    Molar Mass 456.9
    吸湿 Hygroscopic
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO
    安全信息
    R相 R: 22-37/38-41

    Harmful if swallowed.
    Irritating to respiratory system and skin.
    Risk of serious damage to eyes.
    S相 S: 26-39

    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    Wear eye/face protection.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Harmful
    储存 +2°C to +8°C
    避光 Protect from light
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,506153,p38 MAP Kinase Inhibitor IV - CAS 1638-41-1 - Calbiochem

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