merck millipore,默克密理愽
  • merck millipore,默克密理博,AB9604,Anti-Semaphorin 3A Antibody, central region

  • merck millipore,默克密理博,AB9604,Anti-Semaphorin 3A Antibody, central region

    产品名称：Anti-Semaphorin 3A Antibody, central region
    产品型号：AB9604
    Anti-Semaphorin 3A Antibody, central region detects level of Semaphorin 3A & has been published & validated for use in WB.

    merck millipore,默克密理博,AB9604,Anti-Semaphorin 3A Antibody, central region

  • 产品介绍
  • merck millipore,默克密理博,AB9604,Anti-Semaphorin 3A Antibody, central region

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, HWBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB9604
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Semaphorin 3A Antibody, central region
    产品信息
    格式 Affinity Purified
    演示 Liquid in PBS containing 50% glycerol, 1 mg/mL BSA and 0.05% sodium azide.
    应用
    应用 Anti-Semaphorin 3A Antibody, central region detects level of Semaphorin 3A & has been published & validated for use in WB.
    主要应用
    • Western Blotting
    应用说明 Western blot: 1:1,000 on neonatal rat brain and recombinant human Semaphorin 3A/Fc chimera (95/125 kDa). The antibody reacts with the ~95 kDa protein. The suggested antibody diluent is PBS containing 5% non-fat milk and 0.04% Tween 20.

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 Synthetic peptide from the central region of human semaphorin 3A.
    宿主 Rabbit
    特异性 Semaphorin 3A. The immunogen sequence has low homology with other semaphorin family members.
    品种反应性 RatHuman
    Species Reactivity Note It is expected that the antibody will also react with mouse.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_006080.2
    Entrez基因汇总 This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.
    基因符号
    • SEMAL
    • SEMA3A
    • SEMAD
    • SEMAIII
    • SEMA1-PEN
    • semaphorin-like
    • MGC133243
    • SEMA1
    • Hsema-I
    • Hsema-III
    • SemD
    • coll-1
    UniProt编号
    • Q14563
    UniProt汇总 FUNCTION: SwissProt: Q14563 # Induces the collapse and paralysis of neuronal growth cones. Could serve as a ligand that guides specific growth cones by a motility-inhibiting mechanism. Binds to the complex neuropilin-1/plexin-1 (By similarity).
    SIZE: 771 amino acids; 88889 Da
    SUBCELLULAR LOCATION: Secreted (By similarity).
    DOMAIN:SwissProt: Q14563 Strong binding to neuropilin is mediated by the carboxy third of the protein.
    SIMILARITY: Belongs to the semaphorin family. & Contains 1 Ig-like C2-type (immunoglobulin-like) domain. & Contains 1 PSI domain. & Contains 1 Sema domain.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,AB9604,Anti-Semaphorin 3A Antibody, central region

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