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merck millipore,默克密理博,475843,Minocycline, Hydrochloride - CAS 13614-98-7 - Calbiochem
产品名称：Minocycline, Hydrochloride - CAS 13614-98-7 - Calbiochem
产品型号：475843
Semi-synthetic tetracycline derivative effective against tetracycline-resistant staphylococci.
merck millipore,默克密理博,475843,Minocycline, Hydrochloride - CAS 13614-98-7 - Calbiochem
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重要规格表
经验配方 CAS号 C₂₃H₂₇N₃O₇ · HCl 13614-98-7 描述 概述 Semi-synthetic tetracycline derivative effective against tetracycline-resistant staphylococci. A matrix metalloproteinase (MMP) inhibitor shown to inhibit tumor-induced angiogenesis. Inhibits stromelysin (MMP-3; IC50 = 290 µM) but does not inhibit other MMPs such as fibroblast collagenase or gelatinase. Potently inhibits PARP-1 (Ki = 13.4 nM) in a NAD+ - competitive manner. Exhibits anti-inflammatory effects and suppresses T cell proliferation. 产品目录编号 475843 品牌系列 Calbiochem®
同义词 7-Dimethylamino-6-demethyl-6-deoxytetracycline, HCl 参考 参考 Conrad, C.A., et al. 2006. Proc. Natl. Acad, Sci. USA 103, 9685.
Gilbertson-Breading, S., et al. 1995. Cancer Chemother. Pharmacol. 36, 418.
Kloppenburg, M., et al. 1995. Clin. Exp. Immunol. 102, 635.
Preus, H.R., et al. 1995. J. Clin. Periodontol. 22, 380.
Weingart, J.D., et al. 1995. J. Neurosurg. 82, 635.
Tamargo, R.J., et al. 1991. Cancer Res. 51, 672.产品信息 CAS号 13614-98-7 具有ATP竞争性 N 形式 Dark yellow solid Hill配方 C₂₃H₂₇N₃O₇ · HCl 化学配方 C₂₃H₂₇N₃O₇ · HCl Molar Mass 493.9 可逆 N 结构配方图像 生物信息 主靶 Metalloproteinase (MMP) 主靶IC50 290 µM against MMP-3 主靶Ki 13.4 nM against PARP-1 纯度 ≥98% by TLC 理化信息 细胞可渗透 N 溶解度 H₂O GHS安全信息 RTECS QI7630500 安全信息 R相 R: 33-36/37/38-63-64
Danger of cumulative effects.
Irritating to eyes, respiratory system and skin.
Possible risk of harm to the unborn child.
May cause harm to breastfed babies.S相 S: 22-45-36
Do not breathe dust.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Wear suitable protective clothing.储存和货运信息 货运代码 Ambient Temperature Only
毒性 Carcinogenic / Teratogenic
储存 +2°C to +8°C
无需冷冻 No
特殊指南 Unstable in solution; reconstitute just prior to use.
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