merck millipore,默克密理愽
  • merck millipore,默克密理博,420132,JAK2 Inhibitor II - CAS 1837-91-8 - Calbiochem

  • merck millipore,默克密理博,420132,JAK2 Inhibitor II - CAS 1837-91-8 - Calbiochem

    产品名称：JAK2 Inhibitor II - CAS 1837-91-8 - Calbiochem
    产品型号：420132
    The JAK2 Inhibitor II, also referenced under CAS 1837-91-8, controls the biological activity of JAK2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applicatio More>>

    merck millipore,默克密理博,420132,JAK2 Inhibitor II - CAS 1837-91-8 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,420132,JAK2 Inhibitor II - CAS 1837-91-8 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₆H₆Br₆1837-91-8
    描述
    概述 A cell-permeable hexabromocyclohexane compound that interacts with a solvent-accessible pocket near the activation loop of JAK2 and acts as a specific, reversible, and direct inhibitor of JAK2 autophosphorylation (maximal inhibition at 50 µM in BSC-40 cells overexpressing JAK2). Reduces growth hormone-mediated JAK2 activation in γ2A cells that stably express growth hormone receptor and JAK2. Does not block EGFR autophosphorylation in murine fibroblasts.
    产品目录编号 420132
    品牌系列 Calbiochem®
    同义词 1,2,3,4,5,6-Hexabromocyclohexane
    参考
    参考 Sandberg, E.M., et al. 2005. J. Med. Chem. 48, 2526.
    产品信息
    CAS号 1837-91-8
    具有ATP竞争性 N
    形式 Off-white solid
    Hill配方 C₆H₆Br₆
    化学配方 C₆H₆Br₆
    Molar Mass 557.5
    可逆 Y
    结构配方图像
    生物信息
    主靶 JAK2 autophosphorylation
    纯度 ≥ 97% by GC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,420132,JAK2 Inhibitor II - CAS 1837-91-8 - Calbiochem

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