• merck millipore,默克密理博,219478,Cdk4 Inhibitor III - CAS 265312-55-8 - Calbiochem
  • merck millipore,默克密理博,219478,Cdk4 Inhibitor III - CAS 265312-55-8 - Calbiochem

    产品名称:Cdk4 Inhibitor III - CAS 265312-55-8 - Calbiochem
    产品型号:219478
    The Cdk4 Inhibitor III, also referenced under CAS 265312-55-8, controls the biological activity of Cdk4. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applica More>>

    merck millipore,默克密理博,219478,Cdk4 Inhibitor III - CAS 265312-55-8 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,219478,Cdk4 Inhibitor III - CAS 265312-55-8 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₅H₁₂N₂O₂S265312-55-8
    描述
    概述 A cell-permeable dioxobenzothiazole compound that acts a selective Cdk4 inhibitor (IC50 = 6.0 µM for Cdk4/D1 and > 200 µM for Cdk2/A). Exhibit better cytotoxic potential against cancer cells (IC50 = 0.61, 1.08, 0.30, and 1.21 µg/ml against A 549, Col 1, HL-60, and HepG2 tumor cells, respectively) than Cisplatin (Cat. No. 232120).
    产品目录编号 219478
    品牌系列 Calbiochem®
    同义词 5-(N-(4-Methylphenyl)amino)-2-methyl-4,7-dioxobenzothiazole, Ryuvidine
    参考
    参考 Ryu, C.K., et al. 2000. Bioorg. Med. Chem. Lett. 10, 461.
    产品信息
    CAS号 265312-55-8
    具有ATP竞争性 N
    形式 Black-purple solid
    Hill配方 C₁₅H₁₂N₂O₂S
    化学配方 C₁₅H₁₂N₂O₂S
    Molar Mass 284.3
    可逆 N
    结构配方图像
    生物信息
    主靶 Cdk4
    主靶IC50 6.0 µM for Cdk4/D1 and > 200 µM for Cdk2/A
    纯度 ≥90% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,219478,Cdk4 Inhibitor III - CAS 265312-55-8 - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,14-626,EGFR (L858R) Protein, active, 10 µg
下一件merck millipore产品:merck millipore,默克密理博,420132,JAK2 Inhibitor II - CAS 1837-91-8 - Calbiochem



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