• merck millipore,默克密理博,365252,Gö 7874, Hydrochloride - CAS 287935-76-6 - Calbiochem
  • merck millipore,默克密理博,365252,Gö 7874, Hydrochloride - CAS 287935-76-6 - Calbiochem

    产品名称:Gö 7874, Hydrochloride - CAS 287935-76-6 - Calbiochem
    产品型号:365252
    A cell-permeable, potent, reversible, ATP-competitive, and selective inhibitor of protein kinase C (IC₅₀ = 4 nM for rat brain PKC).

    merck millipore,默克密理博,365252,Gö 7874, Hydrochloride - CAS 287935-76-6 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,365252,Gö 7874, Hydrochloride - CAS 287935-76-6 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₇H₂₆N₄O₄ · HCl287935-76-6
    描述
    概述 A cell-permeable, potent, reversible, ATP-competitive, and selective inhibitor of protein kinase C (IC50 = 4 nM for rat brain PKC). Inhibits protein kinase A (IC50 = 510 nM), protein kinase G (IC50 = 4.8 µM), and myosin light chain kinase (IC50 = 120 nM) at much higher concentrations.
    产品目录编号 365252
    品牌系列 Calbiochem®
    同义词 MLCK Inhibitor III
    参考
    参考 Kleinschroth, J., et al. 1995. Bioorg. Med. Chem. Lett. 5, 55.
    产品信息
    CAS号 287935-76-6
    具有ATP竞争性 Y
    形式 Amber solid
    Hill配方 C₂₇H₂₆N₄O₄ · HCl
    化学配方 C₂₇H₂₆N₄O₄ · HCl
    Molar Mass 507.0
    可逆 Y
    结构配方图像
    生物信息
    主靶 PKC
    主靶IC50 4 nM against rat brain PKC
    纯度 ≥97% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

    merck millipore,默克密理博,365252,Gö 7874, Hydrochloride - CAS 287935-76-6 - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,14-517,Blk Protein, active, human, 10 µg
下一件merck millipore产品:merck millipore,默克密理博,MABD136,Anti-Wnt-5a Antibody, clone 6F2



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