merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB5380,Anti-Peripherin Antibody, clone 7C5

  • merck millipore,默克密理博,MAB5380,Anti-Peripherin Antibody, clone 7C5

    产品名称：Anti-Peripherin Antibody, clone 7C5
    产品型号：MAB5380
    Anti-Peripherin Antibody, clone 7C5 detects level of Peripherin & has been published & validated for use in WB, IH.

    merck millipore,默克密理博,MAB5380,Anti-Peripherin Antibody, clone 7C5

  • 产品介绍
  • merck millipore,默克密理博,MAB5380,Anti-Peripherin Antibody, clone 7C5

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, B, H, PoIHC, WBMCulture SupernatantMonoclonal Antibody
    描述
    产品目录编号 MAB5380
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Peripherin Antibody, clone 7C5
    背景信息 Peripherin is a ~57kDa intermediate filament subunit found initially in sensory neurons of the peripheral nervous systems. Subsequently it was found in some sensory and other neurons of the central nervous system and also in PC12 cells. Peripherin is also expressed in certain neuroendocrine tumors and in the insulin producing cells of the pancreas. Peripherin belongs to the Class III family of intermediate filament subunits which includes vimentin, glial fibrillary acidic protein (GFAP) and desmin. Antibodies to peripherin can be used in identifying, classifying, and studying neurons throughout the nervous system. Peripherin is also a good diagnostic marker for ballooned axons seen in Lou Gehrig's disease (Amyotrophic lateral sclerosis) and some neuronally derived tumors. Autoantibodies to peripherin are frequently seen in the sera of patients with diabetes. Peripherin is not related to peripherin/RDS, a protein of the photoreceptor outer membrane mutations of which are causative of certain forms of slow retinal degeneration.
    产品信息
    格式 Culture Supernatant
    控制
    • POSITIVE CONTROL: Sensory neurons of the central or peripheral nervous system; PC12 cells
    演示 Purified immunoglobulin in PBS containing no preservative.
    应用
    应用 Anti-Peripherin Antibody, clone 7C5 detects level of Peripherin & has been published & validated for use in WB, IH.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    应用说明 Immunocytochemistry 1:100. The integrity of the epitope recognized by this antibody is not affected by aldehyde-based fixatives as 8G2; light fixations are still preferred; not tested in paraffin embedded tissue sections.

    Immunoblotting 1:1,000; 57kDa

    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 Recombinant rat peripherin.
    克隆 7C5
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 Peripherin, class III neuronal intermediate filament protein. By western blot, the antibody detects a band migrating at approximately 57 kDa corresponding to peripherin;

    reactive with human, bovine, porcine and rat peripherin by western blot, other species not tested.
    同种型 IgG1κ
    品种反应性 RatBovineHumanPig
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_006262.3
    Entrez基因汇总 This gene encodes a cytoskeletal protein found in neurons of the peripheral nervous system. The encoded protein is a type III intermediate filament protein with homology to other cytoskeletal proteins such as desmin, and is a different protein that the peripherin found in photoreceptors. Mutations in this gene have been associated with susceptibility to amyotrophic lateral sclerosis.
    基因符号
    • NEF4
    • PRPH
    • PRPH1
    • Peripherin.
    • peripherin
    UniProt编号
    • P41219
    UniProt汇总 FUNCTION: SwissProt: P41219 # Class-III neuronal intermediate filament protein.
    SIZE: 470 amino acids; 53651 Da
    SIMILARITY: SwissProt: P41219 ## Belongs to the intermediate filament family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 300 µL

    merck millipore,默克密理博,MAB5380,Anti-Peripherin Antibody, clone 7C5

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