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merck millipore,默克密理博,MABD136,Anti-Wnt-5a Antibody, clone 6F2
产品名称：Anti-Wnt-5a Antibody, clone 6F2
产品型号：MABD136
Detect Wnt-5a using this mouse monoclonal antibody, Anti-Wnt-5a Antibody, clone 6F2 validated for use in western blotting, Immunofluorescence & IHC.
merck millipore,默克密理博,MABD136,Anti-Wnt-5a Antibody, clone 6F2
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H IHC, WB M Ascites Monoclonal Antibody 描述 产品目录编号 MABD136 描述 Anti-Wnt-5a Antibody, clone 6F2 Alternate Names - Protein Wnt-5a
背景信息 The Wnt family of cysteine-rich proteins constitutes a group of ligands known for their roles in development such as cell differentiation, proliferation, migration and embryonic patterning. They have also been implicated in the formation of tumors. Wnts are involved in the stimulation of several signaling cascades that have been divided into two types; the canonical pathway, and the non-canonical pathway. Wnt-5a is considered to be a non-canonical ligand for the Wnt signaling pathway and is a ligand to the frizzled family of seven transmembrane receptors. When interacting with ROR2, Wnt-5a is considered to inhibit tumor formation due to Wnt-5a’s suppression of the canonical Wnt signaling pathway. Wnt-5a is involved in activating cell migration, regulating the motility of melanoma cells, decreasing the proliferation, chondrogenesis, and migration of carcinoma cells, and inhibiting the expression of type II collagen in chondrocytes. Wnt-5a is a requirement to the endothelial differentiation and vascularization of Embryonic Stem Cells, and is also necessary to the development of mammary glands, limb outgrowth, and the genital tubercle. 产品信息 格式 Ascites 控制 - Wnt-5a-hIgGFc transfected HEK293 cell lysate
演示 Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide. 应用 应用 Detect Wnt-5a using this mouse monoclonal antibody, Anti-Wnt-5a Antibody, clone 6F2 validated for use in western blotting, Immunofluorescence & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected Wnt-5a in human lung cancer, thyroid cancer, lymph node, and brain tissues.
Immunofluorescence Analysis: A 1:200-1,000 dilution from a representative lot detected Wnt-5a in PC-12 cells.
Optimal working dilutions must be determined by end user.
生物信息 免疫原品种 Purified recombinant fragment of human Wnt-5a expressed in E. Coli. 克隆 6F2 宿主 Mouse 同种型 IgG1 品种反应性 RatHuman 抗体类型 Monoclonal Antibody 基因符号 - Wnt-5a
- WNT5A
纯化方法 Unpurified UniProt编号 - P41221
产品使用声明 质量保证 Evaluated by Western Blotting in Wnt-5a-hIgGFc transfected HEK293 cell lysate.
Western Blotting Analysis: A 1:500-2000 dilution of this antibody detected Wnt-5a in Wnt-5a-hIgGFc transfected HEK293 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µL
上一件merck millipore产品：merck millipore,默克密理博,365252,Gö 7874, Hydrochloride - CAS 287935-76-6 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,219465,Celastrol, Celastrus scandens - CAS 34157-83-0 - Calbiochem
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