merck millipore,默克密理愽
  • merck millipore,默克密理博,351801,Glucose Transporter Inhibitor III, STF-31 - Calbiochem

  • merck millipore,默克密理博,351801,Glucose Transporter Inhibitor III, STF-31 - Calbiochem

    产品名称：Glucose Transporter Inhibitor III, STF-31 - Calbiochem
    产品型号：351801
    The Glucose Transporter Inhibitor III, STF-31 controls the biological activity of Glucose Transporter.

    merck millipore,默克密理博,351801,Glucose Transporter Inhibitor III, STF-31 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,351801,Glucose Transporter Inhibitor III, STF-31 - Calbiochem

    重要规格表

    经验配方
    C₂₃H₂₅N₃O₃S
    描述
    概述 A cell-permeable sulfonamide that selectively inhibits the growth of VHL-deficient renal cell carcinomas (RCCs) dose-dependently (0-5 µM) by directly targeting glucose transporter 1 (GLUT1), which is up-regulated by HIF (hypoxia-inducible factor) transcription factor in VHL-deficient cells. It elicits decreased oxidative phosphorylation associated with aerobic glycolysis and leads to necrosis, which is consistent with the effect induced by GLUT1 RNA interference. It does not bind to other glucose transporters, and does not inhibit a broad range of 50 tested kinases.
    产品目录编号 351801
    品牌系列 Calbiochem®
    同义词 STF-31
    参考
    参考 Chan, D., et al. 2011. Sci. Transl. Med. 3, 94ra70.
    产品信息
    形式 White solid
    Hill配方 C₂₃H₂₅N₃O₃S
    化学配方 C₂₃H₂₅N₃O₃S
    Molar Mass 423.53
    结构配方图像
    生物信息
    纯度 ≥99% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,351801,Glucose Transporter Inhibitor III, STF-31 - Calbiochem

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