merck millipore,默克密理愽
  • merck millipore,默克密理博,219493,Ceramide Kinase Inhibitor II, NVP-231 - Calbiochem

  • merck millipore,默克密理博,219493,Ceramide Kinase Inhibitor II, NVP-231 - Calbiochem

    产品名称：Ceramide Kinase Inhibitor II, NVP-231 - Calbiochem
    产品型号：219493
    The Ceramide Kinase Inhibitor II, NVP-231 controls the biological activity of Ceramide Kinase. This small molecule/inhibitor is primarily used for Membrane applications.

    merck millipore,默克密理博,219493,Ceramide Kinase Inhibitor II, NVP-231 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,219493,Ceramide Kinase Inhibitor II, NVP-231 - Calbiochem

    重要规格表

    经验配方
    C₂₅H₂₆N₃O₂S
    描述
    概述 A cell-permeable benzothiazole compound that potently inhibits Cer (ceramide) phosphorylation by CerK (Cer Kinase) in a reversible and Cer-, but not ATP-, competitive manner (IC50 = 12 nM; Ki = 7.4 nM) with excellent selectivity over hDAGKα (IC50 = 5 µM) and little or no activity against eight other lipid metabolizing enzymes and kinases (IC50 ≥10 µM) in cell-free enzymatic assays. When applied to live cells in cultures, NVP-231 effectively prevents the binding of Cer to CerK, making cellular Cer more available to other Cer metabolizing enzymes and resulting in an increased GlcCer (glucosylceramide) and SM (sphingomyelin) production in addition to the expected decrease of Cer phosphorylation.
    产品目录编号 219493
    品牌系列 Calbiochem®
    同义词 Adamantane-1-carboxylic acid-(2-benzoylamino-benzothiazol-6-yl)-amide, CerK Inhibitor II, NVP-231
    参考
    参考 Graf, C., et al. 2008. Mol. Pharmacol. 74, 925.
    产品信息
    形式 Tan solid
    Hill配方 C₂₅H₂₆N₃O₂S
    化学配方 C₂₅H₂₆N₃O₂S
    Molar Mass 432.6
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,219493,Ceramide Kinase Inhibitor II, NVP-231 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,06-864,Anti-FLIP Antibody, CT
下一件merck millipore产品：merck millipore,默克密理博,MAB3073,Anti-G Protein Goα Antibody, clone 2A


相关产品

merck millipore,默克密理博,482740,nNOS - PSD-95 Interaction Inhibitor, ZL006 - Calbiochem merck millipore,默克密理博,482740,nNOS - PSD-95 Interaction Inhibitor, ZL006 - Calbiochem

merck millipore,默克密理博,AB5917,Anti-D-Serine Antibody merck millipore,默克密理博,AB5917,Anti-D-Serine Antibody

merck millipore,默克密理博,351801,Glucose Transporter Inhibitor III, STF-31 - Calbiochem merck millipore,默克密理博,351801,Glucose Transporter Inhibitor III, STF-31 - Calbiochem

merck millipore,默克密理博,MAB1904,Anti-Laminin-1 A&B chains Antibody, cross region, clone AL-2 merck millipore,默克密理博,MAB1904,Anti-Laminin-1 A&B chains Antibody, cross region, clone AL-2

merck millipore,默克密理博,06-864,Anti-FLIP Antibody, CT merck millipore,默克密理博,06-864,Anti-FLIP Antibody, CT

merck millipore,默克密理博,MAB3073,Anti-G Protein Goα Antibody, clone 2A merck millipore,默克密理博,MAB3073,Anti-G Protein Goα Antibody, clone 2A

merck millipore,默克密理博,MAB3536,Anti-Lamin B2 Antibody, clone LN43 merck millipore,默克密理博,MAB3536,Anti-Lamin B2 Antibody, clone LN43

merck millipore,默克密理博,PISP30R48,Millicell 悬挂式细胞培养皿, PET, 3.0 µm merck millipore,默克密理博,PISP30R48,Millicell 悬挂式细胞培养皿, PET, 3.0 µm

merck millipore,默克密理博,71086,KOD Hot Start DNA Polymerase merck millipore,默克密理博,71086,KOD Hot Start DNA Polymerase

merck millipore,默克密理博,613424,Tocopherol Set - Calbiochem merck millipore,默克密理博,613424,Tocopherol Set - Calbiochem


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部