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merck millipore,默克密理博,260585,5ʹ-Deoxy-5ʹ-methylthioadenosine - CAS 2457-80-9 - Calbiochem
产品名称：5ʹ-Deoxy-5ʹ-methylthioadenosine - CAS 2457-80-9 - Calbiochem
产品型号：260585
A cell-permeable, reversible, and ATP-competitive naturally-occurring co-product of polyamine biosynthesis that acts as an endogenous substrate of methylthioadenosine phosphorylase (MTAP).
merck millipore,默克密理博,260585,5ʹ-Deoxy-5ʹ-methylthioadenosine - CAS 2457-80-9 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₁₁H₁₅N₅O₃S 2457-80-9 描述 概述 A cell-permeable, reversible, and ATP-competitive naturally-occurring co-product of polyamine biosynthesis that acts as an endogenous substrate of methylthioadenosine phosphorylase (MTAP). Potently inhibits the protein carboxymethyltransferase and induces apoptosis in leukemia U937 cells. Also inhibits FGF-2 receptor tyrosine kinase activity as well as the proliferation of human astrocytes and glioma cells. 产品目录编号 260585 品牌系列 Calbiochem®
同义词 MTA, MeSAdo 参考 参考 Lee, S.H., and Cho, Y.D. 1998. Exp. Cell Res. 240, 282.
Smalheiser, N.R. 1998. Brain Res. Dev. Brain Res. 51, 53.
Joy, A., et al. 1997. Oncogene 14, 171.
Riscoe, M.K., et al. 1984. Biochem. Pharmacol. 33, 3639.产品信息 CAS号 2457-80-9 形式 White solid Hill配方 C₁₁H₁₅N₅O₃S 化学配方 C₁₁H₁₅N₅O₃S Molar Mass 297.3 结构配方图像 生物信息 主靶 protein carboxymethyltranferase 副靶 FGF-2receptor tyrosine kinase activity 纯度 ≥99% by HPLC 理化信息 溶解度 DMF or DMSO GHS安全信息 RTECS AU7410000 安全信息 R相 R: 36/37/38
Irritating to eyes, respiratory system and skin.S相 S: 26-36
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.储存和货运信息 货运代码 Ambient Temperature Only
毒性 Irritant
储存 -20°C
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 1 month at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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下一件merck millipore产品：merck millipore,默克密理博,05-1352,Anti-Histone H2B Antibody, clone 5HH2-2A8
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