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  • merck millipore,默克密理博,420136,JNK Inhibitor IX - CAS 312917-14-9 - Calbiochem

  • merck millipore,默克密理博,420136,JNK Inhibitor IX - CAS 312917-14-9 - Calbiochem

    产品名称：JNK Inhibitor IX - CAS 312917-14-9 - Calbiochem
    产品型号：420136
    The JNK Inhibitor IX, also referenced under CAS 312917-14-9, controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applicatio More>>

    merck millipore,默克密理博,420136,JNK Inhibitor IX - CAS 312917-14-9 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,420136,JNK Inhibitor IX - CAS 312917-14-9 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₀H₁₆N₂OS • H₂O312917-14-9
    描述
    概述 A thienylnaphthamide compound that acts as a potent and ATP binding site-targeting inhibitor of JNK2 and JNK3 (pIC50 = 6.5 and 6.7, respectively) with little or no activity against JNK1, p38α, and a panel of more than 30 other kinases (pIC50 <5.0). In contrast, SP600125 (Cat. Nos. 420119 and 420128) offers little selectivity between JNK1 and JNK3 (pIC50 = 6.4 and 5.9, respectively) under the same assay conditions.
    产品目录编号 420136
    品牌系列 Calbiochem®
    同义词 N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)-1-naphthamide
    参考
    参考 Angell, R.M., et al. 2007. Bioorg. Med. Chem. Lett. 17, 1296.
    产品信息
    CAS号 312917-14-9
    具有ATP竞争性 Y
    形式 Tan solid
    Hill配方 C₂₀H₁₆N₂OS • H₂O
    化学配方 C₂₀H₁₆N₂OS • H₂O
    Molar Mass 332.4
    可逆 N
    结构配方图像
    生物信息
    主靶 JNK2 and JNK3
    主靶IC50 pIC50 = 6.5 and 6.7, against JNK2 and JNK3, respectively
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO
    安全信息
    R相 R: 36/37/38

    Irritating to eyes, respiratory system and skin.
    S相 S: 26-36-45

    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    Wear suitable protective clothing.
    In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Irritant
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,420136,JNK Inhibitor IX - CAS 312917-14-9 - Calbiochem

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