merck millipore,默克密理愽
  • merck millipore,默克密理博,23-045,HIF-1α Protein, 10 µg

  • merck millipore,默克密理博,23-045,HIF-1α Protein, 10 µg

    产品名称：HIF-1α Protein, 10 µg
    产品型号：23-045
    Recombinant human HIF-1α amino acids 331-609, N-terminal c-Myc, GST-tagged. For use in Enzyme Assays. Functions as a substrate in ubiquitination assays.

    merck millipore,默克密理博,23-045,HIF-1α Protein, 10 µg

  • 产品介绍
  • merck millipore,默克密理博,23-045,HIF-1α Protein, 10 µg

    重要规格表

    主要应用 品种 级联部件
    EAHumanSubstrate
    描述
    产品目录编号 23-045
    品牌系列 Upstate
    商名
    • Upstate
    描述 HIF-1α Protein, 10 µg
    长描述 N-terminal c-Myc, GST-tagged, recombinant human HIF-1α amino acids 331-609, expressed by baculovirus in Sf21 insect cells. Purified using glutathione sepharose.
    Alternate Names
    • PAS domain-containing protein 8
    • Hypoxia-inducible factor 1-alpha
    • ARNT-interacting protein
    • Basic-helix-loop-helix-PAS protein MOP1
    • bHLHe78
    背景信息 HIF-1α is the oxygen sensitive subunit of the hypoxia inducible factor HIF-1 which is an essential mediator of the cellular oxygen-signalling pathway. Under hypoxic conditions HIF-1α activates the transcription of over 40 genes, including those that control glucose uptake, metabolism, angiogenesis, erythropoiesis, cell proliferation, and apoptosis. The expression of HIF-1α is commonly increased in a variety of human tumours, and correlates with poor patient prognosis. Under normoxia this protein interacts with the ubiquitin ligase VHL complex, leading to its polyubiquitination and subsequent proteasomal degradation.
    应用
    应用 Recombinant human HIF-1α amino acids 331-609, N-terminal c-Myc, GST-tagged. For use in Enzyme Assays. Functions as a substrate in ubiquitination assays.
    主要应用
    • Enzyme Assay
    生物信息
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    级联部件 Substrate
    Entrez基因编号
    • NM_001530 (GenBank Number)
    纯化方法 Purified using glutathione sepharose.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    包装信息
    数量 10 µg

    merck millipore,默克密理博,23-045,HIF-1α Protein, 10 µg

上一件merck millipore产品：merck millipore,默克密理博,MAB1959Z,Anti-Integrin β1 Antibody, clone P5D2 (Azide Free)| MAB1959
下一件merck millipore产品：merck millipore,默克密理博,407331,ILK inhibitor, Cpd 22 - Calbiochem


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