merck millipore,默克密理愽
  • merck millipore,默克密理博,208920,Calmodulin Kinase IINtide - Calbiochem

  • merck millipore,默克密理博,208920,Calmodulin Kinase IINtide - Calbiochem

    产品名称：Calmodulin Kinase IINtide - Calbiochem
    产品型号：208920
    A potent and specific inhibitor of CaMK II (IC₅₀ = 50 nM for both the total and Ca2+-independent CaMK II activity).

    merck millipore,默克密理博,208920,Calmodulin Kinase IINtide - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,208920,Calmodulin Kinase IINtide - Calbiochem

    重要规格表

    经验配方
    C₁₃₆H₂₄₀N₄₄O₃₉
    描述
    概述 A potent and specific inhibitor of CaMK II (IC50 = 50 nM for both the total and Ca2+-independent CaMK II activity). Exhibits inhibitory activity across converged species, including rat brain, goldfish brain, and Drosophila (IC50 range 100-400 nM). Does not affect the activities of CaMK I, CaMK IV, CaMKK, PKA, or PKC. The peptide sequence corresponds to the inhibitory domain of CaMK IIN.
    产品目录编号 208920
    品牌系列 Calbiochem®
    同义词 KRPPKLGQIGRAKRVVIEDDRIDDVLK-OH
    参考
    参考 Soderling, T.R., et al. 2001. J. Biol. Chem. 276, 3719.
    Chang, B.H., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 10890.
    Pereda, A.E., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 13272.
    产品信息
    具有ATP竞争性 N
    形式 Off-white solid
    配方 Supplied as a trifluoroacetate salt.
    Hill配方 C₁₃₆H₂₄₀N₄₄O₃₉
    化学配方 C₁₃₆H₂₄₀N₄₄O₃₉
    Molar Mass 3115.7
    吸湿 Hygroscopic
    肽序列 H-Lys-Arg-Pro-Pro-Lys-Leu-Gly-Gln-Ile-Gly-Arg-Ala-Lys-Arg-Val-Val-Ile-Glu-Asp-Asp-Arg-Ile-Asp-Asp-Val-Leu-Lys-OH
    可逆 N
    生物信息
    主靶 Cam Kinase-2
    主靶IC50 50 nM for both the total and Ca2+-independent CaMK II activity
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO
    肽序列 H-Lys-Arg-Pro-Pro-Lys-Leu-Gly-Gln-Ile-Gly-Arg-Ala-Lys-Arg-Val-Val-Ile-Glu-Asp-Asp-Arg-Ile-Asp-Asp-Val-Leu-Lys-OH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,208920,Calmodulin Kinase IINtide - Calbiochem

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