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品种反应性 主要应用 宿主 格式 抗体类型 H ICC M Purified Monoclonal Antibody 描述 产品目录编号 05-170 品牌系列 Upstate
商名 - Upstate
描述 Anti-IL-2 Rα Antibody, clone 7G7/B6 产品信息 格式 Purified 控制 - Lung tissue
演示 Protein G Purified immunoglobulin in Protein G Purified immunoglobulin in 0.1M Tris-glycine, pH 7.4, 0.15M NaCl with 0.05% sodium azide as a preservative. 应用 应用 This Anti-IL-2 Rα Antibody, clone 7G7/B6 is validated for use in DB, IC for the detection of IL-2 Rα. 主要应用 - Immunocytochemistry
生物信息 免疫原品种 Whole cells expressing human IL-2 Receptor α 克隆 7G7/B6 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 Recognizes interleukin-2 receptor. 同种型 IgG2a 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_000417.1
Entrez基因汇总 The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. 基因符号 - CD25
- IL2-RA
- IL-2-RA
- OTTHUMP00000044870
- TCGFR
- IL2R
- IDDM10
- p55
- IL2RA
纯化方法 Protein G purfied UniProt编号 - P01589
UniProt汇总 FUNCTION: SwissProt: P01589 # Receptor for interleukin-2.
SIZE: 272 amino acids; 30819 Da
SUBUNIT: Non-covalent dimer of an alpha and a beta chains. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta chain), and a low affinity monomer (alpha chain). The high and intermediate affinity forms also associate with a gamma chain.
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
DISEASE:SwissProt: P01589 # Genetic variations in IL2RA are associated with susceptibility to insulin-dependent diabetes mellitus type 10 (IDDM10) [MIM:601942].
SIMILARITY: SwissProt: P01589 ## Contains 2 Sushi (CCP/SCR) domains.产品使用声明 质量保证 routinely evaluated on ice cold ethanol/acetic acid [95:5] fixed phytohemagglutinin (PHA)-treated Jurkat T lymphocytes 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Lyophilized: 2 years at -20°C; Rehydrated: 6 months at -20°C 包装信息 数量 200 µg
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