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merck millipore,默克密理博,197226,BCRP Inhbitor - Calbiochem
产品名称:BCRP Inhbitor - Calbiochem
产品型号:197226
The BCRP Inhbitor controls the biological activity of BCRP. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
merck millipore,默克密理博,197226,BCRP Inhbitor - Calbiochem
- 产品介绍
重要规格表
经验配方 C₂₂H₁₉N₃O₅ 描述 概述 A non-tetrahydroisoquinoline BCRP specific inhibitor based on the anthranilic acid scaffold, that displays an IC50 of 1.39 µM in a Hoechst 33343 assay in stably transfected MDCK BCRP cells, which is ˜50-fold more potent than novobiocin (IC50 = 65 µM), and shows no effect towards other ATP binding cassette (ABC) transporters P-gp and MRP1 at up to a concentration of 10 µM. It is shown to be an allosteric inhibitor in enzyme kinetics assays in the presence of BCRP specific substrates pheophorbide A and imitanib, and does not lead to a decrease in cell viability up to a concentration of 10 µM. 产品目录编号 197226 品牌系列 Calbiochem®
同义词 N-(4-(2-hydroxyethyl)phenyl)-2-(4-nitrobenzamido)benzamide 参考 参考 Pick, A. et al. 2010. Chem. Med. Chem. 5, 1498.
Klinkhammer, W., et al. 2009. Bioorg. Med. Chem. 17, 2524.产品信息 形式 Off-white solid Hill配方 C₂₂H₁₉N₃O₅ 化学配方 C₂₂H₁₉N₃O₅ Molar Mass 405.4 结构配方图像 生物信息 纯度 ≥95% by HPLC 理化信息 溶解度 DMSO 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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