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品种反应性 主要应用 宿主 格式 抗体类型 M, H, R ICC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 06-1344 描述 Anti-NLRP13 Antibody Alternate Names - NACHT, LRR and PYD domains-containing protein 13
- NLR family, pyrin domain containing 13
- Nucleotide-binding oligomerization domain protein 14
- NACHT, leucine rich repeat and PYD containing 13
- nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 13
- NACHT, LRR and PYD containing protein 13
背景信息 NLRP13, also known as NALP13, is a member of the NALP family of cytoplasmic proteins. NALPs have been associated with activating caspase-1 using toll-like receptors (TLRs) during the immune response. The specific function of NLRP13 is unknown. 产品信息 格式 Affinity Purified 控制 - C2C12 cell lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-NLRP13 Antibody detects level of NLRP13 & has been published & validated for use in WB & IC. 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 Immunocytochemistry Analysis: 1:500 dilution from a previous lot detected NLRP13 in NIH/3T3 cells. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human NLRP13. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 MouseHumanRat Species Reactivity Note Demonstrated to react with human, mouse, and rat. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_789780
Entrez基因汇总 Summary: NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP13, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM]. 基因符号 - NLRP13
- NOD14
- NALP13
- PAN13
纯化方法 Affinity purified UniProt编号 - Q86W25
UniProt汇总 FUNCTION: Involved in inflammation Potential.
SEQUENCE SIMILARITIES: Belongs to the NLRP family.
Contains 1 DAPIN domain.
Contains 7 LRR (leucine-rich) repeats.
Contains 1 NACHT domain.产品使用声明 质量保证 Evaluated by Western Blot in C2C12 cell lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected NLRP13 on 10 µg of C2C12 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,MAB079-1,Anti-S-100 Protein Antibody, clone 15E2E2
下一件merck millipore产品：merck millipore,默克密理博,71757,Overnight Express™ Instant LB Medium - Novagen
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