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merck millipore,默克密理博,14-813,UbcH7 Conjugating Enzyme, 100 µg
产品名称：UbcH7 Conjugating Enzyme, 100 µg
产品型号：14-813
UbcH7 is a class I enzyme which functions in the stress response & the control of transcription factors. The enzyme is ubiquitously expressed with high levels of expression seen in adult muscle.
merck millipore,默克密理博,14-813,UbcH7 Conjugating Enzyme, 100 µg
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重要规格表
Entrez基因编号 品种 Uni Prot编号 NM_182688.1, NM_003343.4 Human P60604 描述 产品目录编号 14-813 品牌系列 Upstate
商名 - Upstate
描述 UbcH7 Conjugating Enzyme, 100 µg 概述 UbcH7 is a class I enzyme which functions in the stress response and the control of transcription factors. The enzyme is ubiquitously expressed with high levels of expression seen in adult muscle. It has been demonstrated to participate in the ubiquitinylation of p53, c-Fos and NF-κB. UbcH7 is one of two E2s (UbcH5 being the other) with which HECT domain proteins interact with UbcH7 being able to efficiently substitute for UbcH5 in E6-AP-dependent ubiquitinylation. Typical enzyme concentration to support conjugation in vitro is 100nM to 1μM depending upon conditions. 应用 应用 UbcH7 is a class I enzyme which functions in the stress response & the control of transcription factors. The enzyme is ubiquitously expressed with high levels of expression seen in adult muscle. 生物信息 纯度 >95% by SDS-PAGE 来源 Recombinant human UbcH7 Conjugating Enzyme expressed in E. coli. 品种 Human Entrez基因编号 - NM_182688.1
- NM_003343.4
Entrez基因汇总 The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse counterpart. This gene is ubiquitously expressed, with high expression seen in adult muscle. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. 基因符号 - UBC7
- UBE2G2
纯化方法 Purified using Ni2+ chelation chromatography with Ni2+ in limiting concentration. UniProt编号 - P60604
UniProt汇总 FUNCTION: SwissProt: P60604 # Catalyzes the covalent attachment of ubiquitin to other proteins. Involved in endoplasmic reticulum-associated degradation (ERAD).
SIZE: 165 amino acids; 18566 Da
SIMILARITY: SwissProt: P60604 ## Belongs to the ubiquitin-conjugating enzyme family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -80°C from date of shipment. Avoid multiple freeze/thaw cycles. After initial defrost, aliquot into individual tubes and refreeze at -80°C. 包装信息 数量 100 µg
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