• merck millipore,默克密理博,317641,Dipeptidylpeptidase IV Inhibitor III - CAS 866396-34-1 - Calbiochem
  • merck millipore,默克密理博,317641,Dipeptidylpeptidase IV Inhibitor III - CAS 866396-34-1 - Calbiochem

    产品名称:Dipeptidylpeptidase IV Inhibitor III - CAS 866396-34-1 - Calbiochem
    产品型号:317641
    The Dipeptidylpeptidase IV Inhibitor III, also referenced under CAS 866396-34-1, controls the biological activity of Dipeptidylpeptidase IV. This small molecule/inhibitor is primarily used for Proteas More>>

    merck millipore,默克密理博,317641,Dipeptidylpeptidase IV Inhibitor III - CAS 866396-34-1 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,317641,Dipeptidylpeptidase IV Inhibitor III - CAS 866396-34-1 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₄H₂₀N₄O₂ • HCl866396-34-1
    描述
    概述 An orally bioavailable dicyanopyrrolidine compound that acts as a slow-binding and active site-targeting inhibitor of DPP IV (IC50 = 106 nM using recombinant human DPP IV and 38, 69, 92, and 100 nM in inhibiting DPP IV activity in plasma from rat, human, monkey, and dog, respectively) with little activity against DPP II, DPP III, DPP VIII, DPP IX, FAP, or APP even at concentrations as high as 30 µM. Reported to lower blood DPP IV activity and augment GLP-1 response in dog and mouse in vivo.
    产品目录编号 317641
    品牌系列 Calbiochem®
    同义词 1-(((1-(Hydroxymethyl)cyclopentyl)amino)acetyl)-2,5-cis-pyrrolidinedicarbonitrile, HCl, DPP IV Inhibitor III
    参考
    参考 Wright, S.W., et al. 2006. J. Med. Chem. 49, 3068.
    产品信息
    CAS号 866396-34-1
    形式 White solid
    Hill配方 C₁₄H₂₀N₄O₂ • HCl
    化学配方 C₁₄H₂₀N₄O₂ • HCl
    Molar Mass 312.8
    吸湿 Hygroscopic
    结构配方图像
    生物信息
    纯度 ≥97% by HPLC
    理化信息
    溶解度 EtOH or H₂O
    安全信息
    S相 S: 22-24/25-36/37/39

    Do not breathe dust.
    Avoid contact with skin and eyes.
    Wear suitable protective clothing, gloves and eye/face protection.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,317641,Dipeptidylpeptidase IV Inhibitor III - CAS 866396-34-1 - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,ST1711,Anti-DFHR Mouse mAb (2B10)
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