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描述 产品目录编号 14-739M 品牌系列 Upstate
商名 - Upstate
描述 TLK2 Protein, active, 250 µg 概述 N-terminal 6His-tagged, recombinant, 388-end, human TLK2. Alternate Names - tousled-like kinase 2
应用 应用 Active, N-terminal 6His-tagged, recombinant, 388-end, human TLK2. For use in Kinase Assays. 主要应用 - Kinase Assay
生物信息 来源 Expressed by baculovirus in Sf21 cells. 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Entrez基因编号 - NM_006852.2
Entrez基因汇总 The Tousled-like kinases, first described in Arabidopsis, are nuclear serine/threonine kinases that are potentially involved in the regulation of chromatin assembly.[supplied by OMIM] 基因符号 - PKU-ALPHA
- TLK2
- MGC44450
- PKU-alpha
蛋白靶 TLK2 纯化方法 Ni2+/NTA-agarose 靶子系列 Misc UniProt编号 - Q86UE8
UniProt汇总 FUNCTION: SwissProt: Q86UE8 # Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S- phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly.
COFACTOR: Magnesium.
SIZE: 772 amino acids; 87661 Da
SUBUNIT: Heterodimerizes with TLK1. Interacts with ASF1A and ASF1B.
SUBCELLULAR LOCATION: Nucleus.
TISSUE SPECIFICITY: Widely expressed. Present in fetal placenta, liver, kidney, pancreas, heart and skeletal muscle. Also found in adult cell lines.
SIMILARITY: SwissProt: Q86UE8 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 6 months at -70°C from date of shipment. For maximum recovery of product, centrifuge original vial prior to removing the cap.
Rapidly thaw the vial under cold water and immediately place on ice. Aliquot unused material into pre-chilled microcentrifuge tubes and immediately snap-freeze the vials in liquid nitrogen prior to re-storage at -70°C.包装信息 数量 250 µg 包装 Also available in 10 μg size (cat#14-739) and in bulk (cat# 14-739-K).
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