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主要应用 品种 来源 CULT Human Recombinant DNA expressed in yeast (S. cerevisiae). 描述 产品目录编号 01-106 品牌系列 Upstate
商名 - Upstate
描述 FGF-2 / basic FGF Protein, Human recombinant 产品信息 演示 PBS, pH 7.4, containing 0.5% BSA and 0.1% CHAPS 应用 应用 The FGF-2 / basic FGF Protein, Human recombinant is available in a 25 µg format. 主要应用 - Cell Culture
生物信息 来源 Recombinant DNA expressed in yeast (S. cerevisiae). 品种 Human Entrez基因编号 - NM_002006.3
Entrez基因汇总 The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. 基因符号 - FGFB
- FGF2
- Prostatropin
- BFGF
- prostatropin
- HBGF-2
物理形式 Liquid 纯化方法 Heparin-Sepharose™ chromatography UniProt编号 - P09038
UniProt汇总 FUNCTION: SwissProt: P09038 # The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors.
SIZE: 155 amino acids; 17254 Da
SUBUNIT: Monomer. Interacts with CSPG4 and FGFBP1. Found in a complex with FGFBP1, FGF1 and FGF2.
SIMILARITY: SwissProt: P09038 ## Belongs to the heparin-binding growth factors family.
MISCELLANEOUS: This protein binds heparin more strongly than does aFGF.产品使用声明 质量保证 Routinely evaluated by Biological Activity Assay. Cultures of fetal bovine heart endothelial (FBHE) cells grown for five days in RD medium containing FBS, heparin, and FGF-2 showed more cells than cultures of FBHE cells grown in same medium without FGF-2. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
包装信息 数量 25 µg
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