merck millipore,默克密理愽
  • merck millipore,默克密理博,203729,(+)-Brefeldin A, Eupenicillium brefeldianum - CAS 20350-15-6 - Calbiochem

  • merck millipore,默克密理博,203729,(+)-Brefeldin A, Eupenicillium brefeldianum - CAS 20350-15-6 - Calbiochem

    产品名称：(+)-Brefeldin A, Eupenicillium brefeldianum - CAS 20350-15-6 - Calbiochem
    产品型号：203729
    Specifically and reversibly blocks translocation of proteins from the endoplasmic reticulum (ER) to the Golgi apparatus without affecting endocytosis or lysosome function.

    merck millipore,默克密理博,203729,(+)-Brefeldin A, Eupenicillium brefeldianum - CAS 20350-15-6 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,203729,(+)-Brefeldin A, Eupenicillium brefeldianum - CAS 20350-15-6 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₆H₂₄O₄20350-15-6
    描述
    概述 Specifically and reversibly blocks translocation of proteins from the endoplasmic reticulum (ER) to the Golgi apparatus without affecting endocytosis or lysosome function. Inhibitor of HDL-mediated cholesterol efflux. Causes disassembly of the Golgi complex and ER swelling in a variety of mammalian cell lines at <40 ng/ml. Blocks binding of ADP-ribosylation factor to the Golgi and inhibits the GDP-GTP exchange. Inhibits the activity of BIG1 and BIG2, the guanine-nucleotide exchange proteins for ADP-ribosylation factors. Also available as a 25 mM solution in DMSO (Cat. No. 500583).
    产品目录编号 203729
    品牌系列 Calbiochem®
    同义词 1,6,7,8,9,11a,12,13,14,14a-Decahydro-1,13-dihydroxy-6-methyl-4H-cyclopent[f]oxacyclotridecin-4-one
    参考
    参考 Yamagi, R., et al. 2000. Proc. Natl. Acad. Sci. USA 97, 2567.
    Moriango, N., et al. 1996. Proc. Natl. Acad. Sci. USA 93, 12856.
    Mendez, A.J. 1995. J. Biol. Chem. 270, 5891.
    Ridgway, N.D., et al. 1995. J. Biol. Chem. 270, 8023.
    Tsai, S.C., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 3063.
    Ktistakis, N.Y., et al. 1992. Nature 356, 344.
    产品信息
    CAS号 20350-15-6
    具有ATP竞争性 N
    形式 White crystalline solid
    Hill配方 C₁₆H₂₄O₄
    化学配方 C₁₆H₂₄O₄
    Molar Mass 280.4
    可逆 Y
    结构配方图像
    生物信息
    主靶 Blocks translocation of proteins from the endoplasmic reticulum (ER) to the Golgi apparatus
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 MeOH
    GHS安全信息
    RTECS GY8410000
    安全信息
    R相 R: 20/21/22

    Harmful by inhalation, in contact with skin and if swallowed.
    S相 S: 36

    Wear suitable protective clothing.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Harmful
    储存 -20°C
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 2 months at -20°C.

    merck millipore,默克密理博,203729,(+)-Brefeldin A, Eupenicillium brefeldianum - CAS 20350-15-6 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,232120,Cisplatin - CAS 15663-27-1 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,AP106X-K,Rabbit Anti-Sheep IgG Affinity Purified (1mg) KC


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