merck millipore,默克密理愽
  • merck millipore,默克密理博,14-383,Rho Assay Reagent (Rhotekin RBD, agarose), 650 µg

  • merck millipore,默克密理博,14-383,Rho Assay Reagent (Rhotekin RBD, agarose), 650 µg

    产品名称：Rho Assay Reagent (Rhotekin RBD, agarose), 650 µg
    产品型号：14-383
    Specifically binds to & precipitates GTP-Rho, but not GDP-Rho from cell lysates. For use in Affinity Binding Assays.

    merck millipore,默克密理博,14-383,Rho Assay Reagent (Rhotekin RBD, agarose), 650 µg

  • 产品介绍
  • merck millipore,默克密理博,14-383,Rho Assay Reagent (Rhotekin RBD, agarose), 650 µg

    描述
    产品目录编号 14-383
    品牌系列 Upstate
    商名
    • Upstate
    描述 Rho Assay Reagent (Rhotekin RBD, agarose), 650 µg
    概述 GST-tagged fusion protein, corresponding to residues 7-89 of mouse Rhotekin Rho Binding Domain, expressed in E.coli and bound to glutathione-agarose. Specifically binds to and precipitates GTP-Rho, but not GDP-Rho from cell lysates.
    产品信息
    演示 650 µg of recombinant protein in 1 mL glutathione-agarose slurry containing 45mM TRIS, pH 7.5, 0.45% Triton X-100, 135mM NaCl, 4.5mM MgCl2, 0.9mM dithiothreitol, 0.09mM PMSF, 0.9 µg/mL aprotinin, 0.9 µg/mL leupeptin, and 10% glycerol.
    应用
    应用 Specifically binds to & precipitates GTP-Rho, but not GDP-Rho from cell lysates. For use in Affinity Binding Assays.
    主要应用
    • Affinity Binding Assay
    生物信息
    来源 Expressed in E. coli
    品种 Mouse
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_033046.2
    • NM_001015055.1
    • NM_001015056.1
    Entrez基因汇总 This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
    基因符号
    • B5
    • RTKN
    • Rhotekin.
    • rhotekin
    UniProt编号
    • Q9BST9
    UniProt汇总 FUNCTION: SwissProt: Q9BST9 # Mediates Rho signaling to activate NF-kappa-B and may confer increased resistance to apoptosis to cells in gastric tumorigenesis. May play a novel role in the organization of septin structures.
    SIZE: 563 amino acids; 62667 Da
    SUBUNIT: Interacts via its C-terminal region with the TAX1BP3 PDZ domain. This interaction facilitates Rho-mediated activation of the c-Fos serum response element (SRE). Interacts with SEPT9. Specifically binds to GTP-bound RHOA, RHOB and RHOC and inhibits their GTPase activity.
    TISSUE SPECIFICITY: Highly expressed in prostate, moderately in kidney, heart, brain, spleen, testis, placenta, small intestine, pancreas, skeletal muscle and peripheral blood leukocytes, and weakly in ovary, colon and thymus. Weakly expressed in all normal cell lines tested. Overexpressed in various cancer cell lines.
    SIMILARITY: SwissProt: Q9BST9 ## Contains 1 PH domain. & Contains 1 REM (Hr1) repeat.
    产品使用声明
    质量保证 Routinely evaluated by precipitating GTP-Rho from 3T3/A31 lysates, subsequent detection by immunoblot analysis using Anti-RhoA, clone 55 (05-778).
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 6 months at -70°C from date of receipt.
    包装信息
    数量 650 µg

    merck millipore,默克密理博,14-383,Rho Assay Reagent (Rhotekin RBD, agarose), 650 µg

上一件merck millipore产品：merck millipore,默克密理博,06-549,Anti-Myc Tag Antibody
下一件merck millipore产品：merck millipore,默克密理博,14-652M,SIK Protein, active, 250 µg


相关产品

merck millipore,默克密理博,567805,Src Kinase Inhibitor I - CAS 179248-59-0 - Calbiochem merck millipore,默克密理博,567805,Src Kinase Inhibitor I - CAS 179248-59-0 - Calbiochem

merck millipore,默克密理博,SF-496,miR-18a-5p; Human, Cyanine 5, RNA Detection Probe,SmartFlare merck millipore,默克密理博,SF-496,miR-18a-5p; Human, Cyanine 5, RNA Detection Probe,SmartFlare

merck millipore,默克密理博,FCMAB204F,Milli-Mark™ Anti-CD66abce-FITC Antibody, clone Kat4c merck millipore,默克密理博,FCMAB204F,Milli-Mark™ Anti-CD66abce-FITC Antibody, clone Kat4c

merck millipore,默克密理博,AB1952P,Anti-Integrin β1 Antibody, cytosolic merck millipore,默克密理博,AB1952P,Anti-Integrin β1 Antibody, cytosolic

merck millipore,默克密理博,06-549,Anti-Myc Tag Antibody merck millipore,默克密理博,06-549,Anti-Myc Tag Antibody

merck millipore,默克密理博,14-652M,SIK Protein, active, 250 µg merck millipore,默克密理博,14-652M,SIK Protein, active, 250 µg

merck millipore,默克密理博,09-722,Anti-XBP1 Antibody merck millipore,默克密理博,09-722,Anti-XBP1 Antibody

merck millipore,默克密理博,HTS017M,ChemiSCREEN™ C5aR Membrane Preparation, recombinant merck millipore,默克密理博,HTS017M,ChemiSCREEN™ C5aR Membrane Preparation, recombinant

merck millipore,默克密理博,17-10523,EZ-Magna Nuclear RIP™ (Native)Nuclear RNA-Binding Protein Immunoprecipitation Kit merck millipore,默克密理博,17-10523,EZ-Magna Nuclear RIP™ (Native)Nuclear RNA-Binding Protein Immunoprecipit...

merck millipore,默克密理博,14-920M,CLK1, active merck millipore,默克密理博,14-920M,CLK1, active


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部