merck millipore,默克密理愽
  • merck millipore,默克密理博,14-652M,SIK Protein, active, 250 µg

  • merck millipore,默克密理博,14-652M,SIK Protein, active, 250 µg

    产品名称：SIK Protein, active, 250 µg
    产品型号：14-652M
    Active, N-terminal 6His-tagged, recombinant, human SIK, amino acids 1-281. For use in Kinase Assays.

    merck millipore,默克密理博,14-652M,SIK Protein, active, 250 µg

  • 产品介绍
  • merck millipore,默克密理博,14-652M,SIK Protein, active, 250 µg

    描述
    产品目录编号 14-652M
    品牌系列 Upstate
    商名
    • Upstate
    描述 SIK Protein, active, 250 µg
    概述 N-terminal 6His-tagged, recombinant, human SIK, amino acids 1-281.
    应用
    应用 Active, N-terminal 6His-tagged, recombinant, human SIK, amino acids 1-281. For use in Kinase Assays.
    主要应用
    • Kinase Assay
    生物信息
    来源 Expressed by baculovirus in Sf21 insect cells.
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_173354.3
    基因符号
    • SIK1
    • SNF1LK
    • MSK
    • msk
    • SIK
    蛋白靶 SIK
    纯化方法 Ni2+/NTA-agarose
    靶子系列 CAMK
    UniProt编号
    • P57059
    UniProt汇总 FUNCTION: SwissProt: P57059 # Transient role during the earliest stages of myocardial cell differentiation and/or primitive chamber formation and may also be important for the earliest stages of skeletal muscle growth and/or differentiation. Potential role in G2/M cell cycle regulation. Inhibits CREB activity by phosphorylating and repressing the CREB-specific coactivators, CRTC1-3 (By similarity).
    COFACTOR: Magnesium.
    SIZE: 783 amino acids; 84902 Da
    SUBUNIT: Binds to and is activated by YWHAZ when phosphorylated on Thr-182.
    SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note=Translocates to the cytoplasm on phosphorylation where it binds binding to YWHAZ.
    PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.
    SIMILARITY: SwissProt: P57059 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily. & Contains 1 protein kinase domain. & Contains 1 UBA domain.
    产品使用声明
    质量保证 Routinely evaluated by phosphorylation of AMARA Substrate Peptide (Catalog# 12-557).
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 6 months at -70°C from date of shipment
    包装信息
    数量 250 µg
    包装 Also available in 10 μg size (cat#14-652) and in bulk (cat# 14-652-K).

    merck millipore,默克密理博,14-652M,SIK Protein, active, 250 µg

上一件merck millipore产品：merck millipore,默克密理博,14-383,Rho Assay Reagent (Rhotekin RBD, agarose), 650 µg
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