• merck millipore,默克密理博,567805,Src Kinase Inhibitor I - CAS 179248-59-0 - Calbiochem
  • merck millipore,默克密理博,567805,Src Kinase Inhibitor I - CAS 179248-59-0 - Calbiochem

    产品名称:Src Kinase Inhibitor I - CAS 179248-59-0 - Calbiochem
    产品型号:567805
    The Src Kinase Inhibitor I, also referenced under CAS 179248-59-0, controls the biological activity of Src Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylati More>>

    merck millipore,默克密理博,567805,Src Kinase Inhibitor I - CAS 179248-59-0 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,567805,Src Kinase Inhibitor I - CAS 179248-59-0 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₂H₁₉N₃O₃179248-59-0
    描述
    概述 A 4′-phenoxy substituted 4-anilinoquinazoline compound that acts as a potent, selective, dual site, cell-permeable, reversible and ATP-competitive inhibitor of Src family tyrosine kinases (IC50 = 44 nM and 88 nM for Src and Lck, respectively). Shown to simultaneously interact with both the ATP- and peptide-binding sites. Inhibits VEGFR2 and c-fms tyrosine kinases at much higher concentrations (IC50 = 0.32 µM and 30 µM, respectively).
    产品目录编号 567805
    品牌系列 Calbiochem®
    同义词 4-(4ʹ-Phenoxyanilino)-6,7-dimethoxyquinazoline, VEGFR Tyrosine Kinase Inhibitor XV, VEGFR2 Kinase Inhibitor XIII
    参考
    参考 Tian, G., et al. 2001. Biochemistry 40, 7084.
    产品信息
    CAS号 179248-59-0
    具有ATP竞争性 Y
    形式 Off-white solid
    Hill配方 C₂₂H₁₉N₃O₃
    化学配方 C₂₂H₁₉N₃O₃
    Molar Mass 373.4
    可逆 Y
    结构配方图像
    生物信息
    主靶 Src
    主靶IC50 44 nM and 88 nM for Src and Lck, respectively
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,567805,Src Kinase Inhibitor I - CAS 179248-59-0 - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,SLHV013SL,Millex-HV 过滤器,0.45 µm,PVDF,13 mm,环氧乙烷灭菌
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