merck millipore,默克密理愽
  • merck millipore,默克密理博,04-1542,Anti-ETS1 DBD Antibody, clone 1ET 7F2

  • merck millipore,默克密理博,04-1542,Anti-ETS1 DBD Antibody, clone 1ET 7F2

    产品名称：Anti-ETS1 DBD Antibody, clone 1ET 7F2
    产品型号：04-1542
    Use Anti-ETS1 DBD Antibody, clone 1ET 7F2 (Mouse Monoclonal Antibody) validated in WB to detect ETS1 DBD also known as Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1, ets protein.

    merck millipore,默克密理博,04-1542,Anti-ETS1 DBD Antibody, clone 1ET 7F2

  • 产品介绍
  • merck millipore,默克密理博,04-1542,Anti-ETS1 DBD Antibody, clone 1ET 7F2

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, H, MWBMAscitesMonoclonal Antibody
    描述
    产品目录编号 04-1542
    描述 Anti-ETS1 DBD Antibody, clone 1ET 7F2
    Alternate Names
    • -ETS-1 protein, ETS 1, ETS1, EWSR 2, EWSR2
    • Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1
    • ets protein
    • v-ets avian erythroblastosis virus E2 oncogene homolog 1
    • v-ets avian erythroblastosis virus E26 oncogene homolog 1
    • v-ets erythroblastosis virus E26 oncogene homolog 1
    • v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
    背景信息 ETS1 belongs to a family of transcription factors that regulates expression of several genes participating in extracellular matrix remodeling. Members of the ETS family regulate a variety of genes involved in stem cell development, cell senescence, and tumorigenesis. ETS1 is typically absent in healthy gastric epithelium, but expressed in many gastric carcinomas and oral squamus cell carcinomas.
    This family of transcription factors contains 2 main domains; a transactivation domain (TA), and a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes. This DNA-Binding-Domain is highly conserved among ETS family members.
    产品信息
    格式 Ascites
    控制
    • HL60 cell lysate
    演示 Unpurified mouse monoclonal IgG1κ in preservative-free ascites.
    应用
    应用 Use Anti-ETS1 DBD Antibody, clone 1ET 7F2 (Mouse Monoclonal Antibody) validated in WB to detect ETS1 DBD also known as Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1, ets protein.
    主要应用
    • Western Blotting
    生物信息
    免疫原品种 Linear peptide corresponding to human ETS1 DBD.
    表位 Unknown
    克隆 clone 1ET 7F2
    宿主 Mouse
    特异性 This antibody recognizes ETS1.
    同种型 IgG1κ
    品种反应性 RatHumanMouse
    Species Reactivity Note Demonstrated to react with human. Predicted to react with mouse and rat based on 100% sequence homology.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_005229.1
    Entrez基因汇总 ETS transcriptions factors, such as ETS1, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al., 2007 [PubMed 17986575]).[supplied by OMIM].
    基因符号
    • EWSR2
    • ETS1
    • ETS-1
    • p54
    • ETS-1 protein: ETS 1: ETS1
    • EWSR 2
    纯化方法 Unpurified
    UniProt编号
    • P14921
    UniProt汇总 FUNCTION: Transcription factor.

    SIZE: 441 amino acids; 50408 Da

    SUBUNIT: Binds to DAXX. Interacts with UBE2I.

    SUBCELLULAR LOCATION: Nucleus.

    PTM: Sumoylated on Lys-15 and Lys-227, preferentially by SUMO2; which inhibits transcriptional activity (By similarity). & Ubiquitinated; which induces proteasomal degradation (By similarity).

    DISEASE: ETS is responsible for erythroblast and fibroblast transformation. The juxtaposition of the interferon and c-ETS-1 proto-oncogene may be involved in the pathogenesis of human monocytic leukemia.

    SIMILARITY: Belongs to the ETS family. & Contains 1 ETS DNA-binding domain. & Contains 1 PNT (pointed) domain.
    产品使用声明
    质量保证 Evaluated by Western Blot in HL60 cell lysate.

    Western Blot Analysis: 1:1,000 dilution of this antibody detected ETS1 DBD on 10 µg of HL60 cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at -20°C from date of receipt.
    Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,04-1542,Anti-ETS1 DBD Antibody, clone 1ET 7F2

上一件merck millipore产品：merck millipore,默克密理博,HTS204RTA,Ready-to-Assay™ Y4 Neuropeptide Y Receptor Frozen Cells
下一件merck millipore产品：merck millipore,默克密理博,ABT187,Anti-TRPM8 Antibody


相关产品

merck millipore,默克密理博,219364,Cathepsin B, Human Liver merck millipore,默克密理博,219364,Cathepsin B, Human Liver

merck millipore,默克密理博,04-591,Anti-FAK Antibody, rabbit monoclonal, clone EP695Y merck millipore,默克密理博,04-591,Anti-FAK Antibody, rabbit monoclonal, clone EP695Y

merck millipore,默克密理博,539109,PAR-2 Agonist I - Calbiochem merck millipore,默克密理博,539109,PAR-2 Agonist I - Calbiochem

merck millipore,默克密理博,MABE332,Anti-c-ErbB2/c-Neu Antibody, clone 9G6 merck millipore,默克密理博,MABE332,Anti-c-ErbB2/c-Neu Antibody, clone 9G6

merck millipore,默克密理博,HTS204RTA,Ready-to-Assay™ Y4 Neuropeptide Y Receptor Frozen Cells merck millipore,默克密理博,HTS204RTA,Ready-to-Assay™ Y4 Neuropeptide Y Receptor Frozen Cells

merck millipore,默克密理博,ABT187,Anti-TRPM8 Antibody merck millipore,默克密理博,ABT187,Anti-TRPM8 Antibody

merck millipore,默克密理博,AB3365P,Anti-Resistin-like Molecule α Antibody merck millipore,默克密理博,AB3365P,Anti-Resistin-like Molecule α Antibody

merck millipore,默克密理博,SF-1682,EXT2; Human, Cyanine 5 RNA Detection Probe,SmartFlare merck millipore,默克密理博,SF-1682,EXT2; Human, Cyanine 5 RNA Detection Probe,SmartFlare

merck millipore,默克密理博,S7750,TRAPeze ELISA Telomerase Detection Kit, strip well plates merck millipore,默克密理博,S7750,TRAPeze ELISA Telomerase Detection Kit, strip well plates

merck millipore,默克密理博,AB5926,Anti-Potassium Channel Kv1.4 Antibody merck millipore,默克密理博,AB5926,Anti-Potassium Channel Kv1.4 Antibody


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部