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描述 概述 Native cathepsin B from human liver, purified by affinity chromatography. The most investigated enzyme of all lysosomal cysteine proteases. Upregulation and secretion of cathepsin B have been shown to occur in many types of tumors and to correlate positively with their invasive and metastatic capabilities. Cathepsin B is shown to facilitate tumor invasion by dissolving extracellular barriers. 产品目录编号 219364 品牌系列 Calbiochem®
参考 参考 Kostoulas, G., et al. 1999. FEBS Lett. 455, 286.
Berquim, I.M., and Sloane, B.F. 1996. Adv. Exp. Med. Biol. 389, 281.
Keppler, D., et al. 1994. Biochim. Biophys. Acta. 1226, 117.
Musil, D., et al. 1991. EMBO J. 10, 2321.
Sloane B.F. 1990. Semin. Cancer Biol. 1, 137.产品信息 CAS号 9047-22-7 EC号 3.4.22.1 形式 Liquid 配方 In 50 mM sodium acetate buffer, 1 mM EDTA, pH 5.0. Molar Mass 27500 生物信息 纯度 >95% by SDS-PAGE 来源 Prepared from tissue of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. 特异活性 ≥50 U/mg protein 浓缩标签 Please refer to vial label for lot-specific concentration
理化信息 pH值 optimum 3.5 - 6.0 储存和货运信息 货运代码 Dry Ice Only
毒性 Standard Handling
储存 ≤ -70°C
避免冻结 / 解冻 Avoid freeze/thaw
无需冷冻 No
特殊指南 Following initial thaw, aliquot and freeze (-70°C).
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