merck millipore,默克密理博,SF-407,RB1; Human, Cyanine 5, RNA Detection Probe,SmartFlare

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Merck Millipore 默克密理愽

Entrez Gene Number	Species Reactivity
NM_000321.2	H

描述
产品目录编号	SF-407
商名	SmartFlare
描述	RB1; Human, Cyanine 5, RNA Detection Probe \| SmartFlare
Alternate Names	OSRC RB pRb
背景信息	With SmartFlare™ RNA Detection probes, you can detect RNA in LIVE CELLS with ease. With just an overnight incubation of RB1; Human, Cyanine 5, RNA Detection Probe you can detect the presence of RB1 within your cells. Certain genes have been identified whose function appears to be the supression of tumor formation and are therefore classified as tumor suppressor genes. One such gene has been linked to the hereditary cancer retinoblastoma. The retino-blastoma (Rb) gene encodes a protein of 928 amino acids which is found predominantly in the nucleus and has the capability of binding to DNA. The Rb protein may be modified by phosphorylation but while there are several potential sites for N-linked glycosylation, no modification has been detected. The Rb protein has been reported as having apparent molecular weights of ~105 kDa, ~100-114 kDa, and ~102 or ~104 kDa which are antigenically related. The Rb protein has been detect in at least 20 different common laboratory cell lines with the exception of retinoblastoma cells. The malignant trans-formation of cells is caused by inactivation of the gene by mutation but also by inactivation of the Rb protein resulting from binding to the adenovirus E1A protein or SV40 T antigen.

产品信息
格式	Cyanine 5
演示	Lyophilized

应用
应用	Use SmartFlare RNA Detection probes to measure gene expression in live cells. With an overnight incubation of SmartFlare RB1, Human, Cyanine 5, you can detect RB1 RNA levels within your cells.
主要应用	RNA Detection

产品使用声明
质量保证	SmartFlare Probes have been tested in a buffer system to detect the release of the fluorophore in the presence of a complimentary base pair sequence for each lot to confirm target specificity. SmartFlare Probes have also been tested in a cell model system and demonstrated increased fluorescence in cells expressing the target compared to a negative SmartFlare Scramble Control.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Store at 2–8°C in lyophilized format ONLY. Room temperature is required for reconstituted product.

包装信息
数量	250 reactions

merck millipore,默克密理博,SF-407,RB1; Human, Cyanine 5, RNA Detection Probe,SmartFlare

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