merck millipore,默克密理愽
  • merck millipore,默克密理博,528116,PI 3-Kα Inhibitor VIII - CAS 372196-77-5 - Calbiochem

  • merck millipore,默克密理博,528116,PI 3-Kα Inhibitor VIII - CAS 372196-77-5 - Calbiochem

    产品名称：PI 3-Kα Inhibitor VIII - CAS 372196-77-5 - Calbiochem
    产品型号：528116
    The PI 3-Kα Inhibitor VIII controls the biological activity of PI 3-Kα. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

    merck millipore,默克密理博,528116,PI 3-Kα Inhibitor VIII - CAS 372196-77-5 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,528116,PI 3-Kα Inhibitor VIII - CAS 372196-77-5 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₆H₁₄N₅O₄SBr • HCl • 2H₂O372196-77-5
    描述
    概述 A cell-permeable imidazopyridine compound that acts as a highly potent and ATP-competitive DNA-PK and p110α-selective PI3-K inhibitor (IC50 = 0.3, 40, 100, and 850 nM for p110α, p110γ, PI 3-K C2β, and p110β, respectively). Shown to effectively block cellular PI3-K/Akt signaling and inhibit tumor growth both in vitro (IC50 ≤58 nM in MCF7, MCF7 ADR-res, HeLa, A375, and A549 cultures) and in mice in vivo (62% inhibition of HeLa xenograft in 2 weeks, 50 mg/kg/day, i.p.).
    产品目录编号 528116
    品牌系列 Calbiochem®
    同义词 N-((1E)-(6-Bromoimidazo[1,2-a]pyridin-3-yl)methylene)-Nʹ-methyl-Nʹʹ-(2-methyl-5-nitrobenzene)sulfonohydrazide, HCl, PI 3-K Inhibitor VIII, PIK-75
    参考
    参考 Kim, S., et al. 2007. Blood 110, 4206.
    Hayakawa, M., et al. 2007. Bioorg. Med. Chem. 15, 5837.
    Knight, Z.A., et al. 2007. Cell 125, 733.
    产品信息
    CAS号 372196-77-5
    形式 Pale yellow solid
    Hill配方 C₁₆H₁₄N₅O₄SBr • HCl • 2H₂O
    化学配方 C₁₆H₁₄N₅O₄SBr • HCl • 2H₂O
    Molar Mass 524.8
    吸湿 Hygroscopic
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Regulatory Review
    储存 +2°C to +8°C
    避光 Protect from light
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,528116,PI 3-Kα Inhibitor VIII - CAS 372196-77-5 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,05-760,Anti-Fibrinogen γ' Antibody, CT, clone 2.G2.H9
下一件merck millipore产品：merck millipore,默克密理博,SF-407,RB1; Human, Cyanine 5, RNA Detection Probe,SmartFlare


相关产品

merck millipore,默克密理博,MR-121-D,EmbryoMax KSOM Medium (1X) w/ 1/2 Amino Acids & Phenol Red merck millipore,默克密理博,MR-121-D,EmbryoMax KSOM Medium (1X) w/ 1/2 Amino Acids & Phenol Red

merck millipore,默克密理博,436305,Linoleic Acid - CAS 60-33-3 - Calbiochem merck millipore,默克密理博,436305,Linoleic Acid - CAS 60-33-3 - Calbiochem

merck millipore,默克密理博,489477,LSD1 Inhibitor II, S2101 - Calbiochem merck millipore,默克密理博,489477,LSD1 Inhibitor II, S2101 - Calbiochem

merck millipore,默克密理博,09-868,Anti-PHD finger protein 8 Antibody merck millipore,默克密理博,09-868,Anti-PHD finger protein 8 Antibody

merck millipore,默克密理博,05-760,Anti-Fibrinogen γ' Antibody, CT, clone 2.G2.H9 merck millipore,默克密理博,05-760,Anti-Fibrinogen γ' Antibody, CT, clone 2.G2.H9

merck millipore,默克密理博,SF-407,RB1; Human, Cyanine 5, RNA Detection Probe,SmartFlare merck millipore,默克密理博,SF-407,RB1; Human, Cyanine 5, RNA Detection Probe,SmartFlare

merck millipore,默克密理博,PP64,IgG, Rabbit merck millipore,默克密理博,PP64,IgG, Rabbit

merck millipore,默克密理博,AB5022,Anti-Taurine (No Gluteraldehyde) Antibody merck millipore,默克密理博,AB5022,Anti-Taurine (No Gluteraldehyde) Antibody

merck millipore,默克密理博,MABC184,Anti-SDF-1 Antibody, clone K15C, Azide free merck millipore,默克密理博,MABC184,Anti-SDF-1 Antibody, clone K15C, Azide free

merck millipore,默克密理博,324890,E-64 Protease Inhibitor - CAS 66701-25-5 - Calbiochem merck millipore,默克密理博,324890,E-64 Protease Inhibitor - CAS 66701-25-5 - Calbiochem


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部