- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
-
-
merck millipore,默克密理博,MABC184,Anti-SDF-1 Antibody, clone K15C, Azide free
产品名称：Anti-SDF-1 Antibody, clone K15C, Azide free
产品型号：MABC184
Detect SDF using this mouse monoclonal antibody, Anti-SDF-1 Antibody, clone K15C, Azide free validated for use in western blotting, IHC, Neutralizing & ELISA.
merck millipore,默克密理博,MABC184,Anti-SDF-1 Antibody, clone K15C, Azide free
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M, H ELISA, WB, IHC M Purified Monoclonal Antibody 描述 产品目录编号 MABC184 描述 Anti-SDF-1 Antibody, clone K15C, Azide free Alternate Names - PBSF
- Stromal cell-derived factor 1
- SDF-1
- hSDF-1
- C-X-C motif chemokine 12
- Intercrine reduced in hepatomas
- IRH
- hIRH
- Pre-B cell growth-stimulating factor
背景信息 Stromal cell-derived factor 1 (SDF-1) is also known as C-X-C motif chemokine 12 (CXCL12), Intercrine reduced in hepatomas (IRH), and Pre-B cell growth-stimulating factor (PBSF). SDF-1 is a chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. SDF-1 stimulates migration of monocytes and T-lymphocytes through its receptors, CXCR4 and CXCR7, and decreases monocyte adherence to surfaces coated with ICAM-1. SDF-1 plays a protective role after myocardial infarction, has critical functions during embryonic development and is required for B-cell lymphopoiesis, myelopoiesis in bone marrow and heart ventricular septum formation. Isoform Alpha and isoform Beta are ubiquitously expressed, with highest levels detected in liver, pancreas and spleen. Isoform Gamma is mainly expressed in heart. Isoform Delta, isoform Epsilon and isoform Theta have highest expression levels in pancreas. 产品信息 格式 Purified 控制 - HEPG2 cell lysate
演示 Purified mouse monoclonal IgG2aκ in buffer containing PBS without preservatives. 应用 应用 Detect SDF using this mouse monoclonal antibody, Anti-SDF-1 Antibody, clone K15C, Azide free validated for use in western blotting, IHC, Neutralizing & ELISA. 主要应用 - ELISA
- Western Blotting
- Immunohistochemistry
应用说明 Western Blotting Analysis: 0.375 µg/mL from a representative lot detected SDF-1 in 10 µg of HeLa and RAW264.7 cell lysates.
Western Blotting Analysis: A representative lot from an independent laboratory detected SDF-1alpha, SDF-1beta, and SDF-IP10 chimera, but not IP-10, IL-8, MDC, MIP-1b, eotaxin, and RANTES in WB (Coulomb-L'Hermin, A., et al. (1999). Proc Natl Acad Sci USA. 96(15):8585-8590.).
ELISA Analysis: A representative lot from an independent laboratory detected SDF-1alpha, SDF-1beta, and SDF-IP10 chimera, but not IP-10, IL-8, MDC, MIP-1b, eotaxin, and RANTES in ELISA (Coulomb-L'Hermin, A., et al. (1999). Proc Natl Acad Sci USA. 96(15):8585-8590.).
Immunohistochemistry Analysis: A representative lot from an independent laboratory detected SDF-1 in human fetal liver, lung, and kidney tissues (Coulomb-L'Hermin, A., et al. (1999). Proc Natl Acad Sci USA. 96(15):8585-8590.).
Neutralization Analysis: A representative lot from an independent laboratory attenuates the increased growth of MCF-7-ras tumor development in the presence of CAFs, decreases angiogenesis, and reduced recruitment of EPCs in tumors (Orimo, A., et al. (2005). Cell. 121(3):335-348.).
Immunhistochemistry Analysis: A representative lot from an independent laboratory detected SDF-1 in epidermal Dendritic Cells (DC) in normal and autoimmune diseased skin tissue (Pablos, J. L., et al. (1999). Am J Pathol. 155(5):1577-1586.).
Immunohistochemistry Analysis: A representative lot from an independent laboratory detected SDF-1 in mucosal surfaces of small intestine tissue, rectal tissue, vaginal tissue, and endocervical tissue (Agace, W. W., et al. (2000). Curr Biol. 10(6):325-328.).
Immunohistochemistry Analysis: A representative lot from an independent laboratory detected SDF-1 in mouse bone marrow sections (Dar, A., et al (2005). Nat Immunol. Epub 2005.).
生物信息 免疫原品种 BSA-conjugated linear peptide corresponding to human SDF-1. 表位 N-terminus 克隆 K15C 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 This antibody recognizes the N-terminus of SDF-1. This antibody should detected SDF-1alpha and SDF-1beta. 同种型 IgG2aκ 品种反应性 MouseHuman 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_000600.1
基因符号 - SDF1B
- CXCL12
- SDF1
- SDF1A
纯化方法 Protein G purified UniProt编号 - P48061
产品使用声明 质量保证 Evaluated by Western Blotting in HEPG2 cell lysate.
Western Blotting Analysis: 0.375 µg/mL of this antibody detected SDF-1 in 10 µg of HEPG2 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,AB5022,Anti-Taurine (No Gluteraldehyde) Antibody
下一件merck millipore产品：merck millipore,默克密理博,324890,E-64 Protease Inhibitor - CAS 66701-25-5 - Calbiochem
相关产品
merck millipore,默克密理博,05-760,Anti-Fibrinogen γ' Antibody, CT, clone 2.G2.H9
merck millipore,默克密理博,528116,PI 3-Kα Inhibitor VIII - CAS 372196-77-5 - Calbiochem
merck millipore,默克密理博,SF-407,RB1; Human, Cyanine 5, RNA Detection Probe,SmartFlare
merck millipore,默克密理博,PP64,IgG, Rabbit
merck millipore,默克密理博,AB5022,Anti-Taurine (No Gluteraldehyde) Antibody
merck millipore,默克密理博,324890,E-64 Protease Inhibitor - CAS 66701-25-5 - Calbiochem
merck millipore,默克密理博,07-145,Anti-phospho-Histone H3 (Ser28) Antibody
merck millipore,默克密理博,AB5547,Anti-GRIP1 Antibody
merck millipore,默克密理博,AB9232-200UL,Anti-Potassium Channel EAG-1 Antibody