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品种反应性 主要应用 宿主 格式 抗体类型 H, M WB M Purified Monoclonal Antibody 描述 产品目录编号 MABT391 描述 Anti-Myosin-10 Antibody, clone 5H4.1 Alternate Names - NMMHC-IIB
- Myosin-10
- Cellular myosin heavy chain, type B
- Myosin heavy chain 10
- Myosin heavy chain, non-muscle Iib
- Non-muscle myosin heavy chain B
- NMMHC-B
- Non-muscle myosin heavy chain Iib
- NMMHC II-b
背景信息 Myosin-10, also known as Cellular myosin heavy chain, type B, Myosin heavy chain 10, Myosin heavy chain, non-muscle IIb, Non-muscle myosin heavy chain B, NMMHC-B, Non-muscle myosin heavy chain IIb, or NMMHC-IIB, and encoded by the gene MYH10, is a myosin protein found in non-muscle cells. Often called cellular myosin, Myosin-10 appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. For instance Mysoin-10, during cell spreading, plays an important role in cytoskeleton reorganization, focal contacts and lamellipodial extension. Additionally, Myosin-10 is involved in many developmental and cellular functions including: axon guidance, retina development, cerebellar Purkinje cell layer development, exocytosis, embryonic development, mitotic cytokinesis, neuron migration, nuclear migration, regulation of cell shape, retina development, cardiac myofibril assembly, and ventricular cardiac muscle cell and adult heart development. Myosin-10 is localized to cell projections and lamellipodia. Myosin-10 is expressed in many cells and particularly in neurons in the cerebellum, spinal cord, and retina. 产品信息 格式 Purified 演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect Myosin-10 using this Anti-Myosin-10 Antibody, clone 5H4.1 validated for use in western blotting. 主要应用 - Western Blotting
应用说明 Western Blotting Analysis: 0.5 µg/mL from a representative lot detected Myosin-10 in 10 µg of HUVEC cell lysate. 生物信息 免疫原品种 GST-tagged recombinant protein corresponding to human Myosin-10. 克隆 5H4.1 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG1κ 品种反应性 HumanMouse 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_001242941
基因符号 - MYH10
纯化方法 Protein G purified UniProt编号 - P35580
产品使用声明 质量保证 Evaluated by Western Blotting in C2C12 cell lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected Myosin-10 in 10 µg of C2C12 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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