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merck millipore,默克密理博,MABT171,Anti-MMP-9 (Active) Antibody, clone 4A3
产品名称:Anti-MMP-9 (Active) Antibody, clone 4A3
产品型号:MABT171
This Anti-MMP-9 (Active) Antibody, clone 4A3 is validated for use in Western Blotting, IHC for the detection of MMP-9 (Active).
merck millipore,默克密理博,MABT171,Anti-MMP-9 (Active) Antibody, clone 4A3
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB M Purified Monoclonal Antibody 描述 产品目录编号 MABT171 描述 Anti-MMP-9 (Active) Antibody, clone 4A3 Alternate Names - GELB
- Matrix metalloproteinase-9
- MMP-9
- 92 kDa gelatinase
- 92 kDa type IV collagenase
- Gelatinase B
背景信息 Matrix metalloproteinase 9 (MMP-9), a member of the peptidase M10A family, is a multidomain zinc metalloproteinase enzyme, which is highly expressed in neurons and glia of the hippocampus, cerebral cortex, and cerebellum. The active MMP-9 is formed upon cell stimulation by enzymatic cleavage of the precursor, proMMP-9. Because of its function in tissue degradation, MMP-9 is tightly regulated by multiple mechanisms, including glycosylation, inhibition by TIMP1, internalization, and sequestration. MMP-9 plays an important role in long-term potentiation, synaptic plasticity, and memory. Several studies have reported an increase in levels of MMP-9 after CNS injury, as well during the development of various cancers. 产品信息 格式 Purified 控制 - Active form of MMP-9
演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 This Anti-MMP-9 (Active) Antibody, clone 4A3 is validated for use in Western Blotting, IHC for the detection of MMP-9 (Active). 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Western Blot Analysis: A representative lot from an independent laboratory detected the active form of MMP-9 in WB (Duncan, M. E., et al. 1998. Eur J Biochem. 258(1):37-43).
Immunohistochemistry Analysis: A representative lot from an independent laboratory detected the active form of MMP-9 in oesophageal cancer tissues (Duncan, M. E., et al. 1998. Eur J Biochem. 258(1):37-43).生物信息 免疫原品种 Ovalbumin-conjugated linear peptide corresponding to the N-terminus of human MMP-9 (Active). 表位 N-terminus 克隆 4A3 宿主 Mouse 特异性 This antibody recognizes the N-terminus of MMP-9 (Active). 同种型 IgG1κ 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_004985
基因符号 - CLG4B
- MMP9
纯化方法 Protein G purified UniProt编号 - P14780
产品使用声明 质量保证 Evaluated by Western Blot with the active form of MMP-9.
Western Blot Analysis: A 1:250 dilution from a reprsentative lot detected the active form of MMP-9 in WB.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 200 µL
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