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品种反应性 主要应用 宿主 格式 抗体类型 H, M, R IHC, WB Rb Purified Polyclonal Antibody 描述 产品目录编号 AB15138 描述 Anti-Nogo Receptor Antibody Alternate Names - Rtn4r
- Reticulon-4 receptor
- Nogo receptor
- NgR
- Nogo-66 receptor
- Nogor
背景信息 Axons are essential for neuronal communication but they do not regenerate after injury to the adult mammalian brain or spinal cord. Failed regeneration is due in part to the production of a potent axonal growth inhibitor, Nogo, by myelinating cells. The finding of a high affinity axonal receptor for the extracellular domain of Nogo provides the first insight into the basis of Nogo action. Disrupting the interaction of Nogo with the Nogo-66 receptor may facilitate axonal regeneration in vivo. The protein is dubbed the Nogo receptor because it binds with several other proteins that block neural growth. It is found to be ubiquitous in the brain and spinal cord. 产品信息 格式 Purified 控制 - Mouse cerebellum lysate
演示 Purified in PBS with 0.1% NaN3 应用 应用 Anti-Nogo Receptor Antibody detects level of Nogo Receptor & has been published & validated for use in WB, IH. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Non-Lot Specific Tested Application 1:
Immunohistochemistry: Working dilutions of 1:50-1:500 in rat brain and spinal cord (paraffin embedded)
生物信息 免疫原品种 Recombinant protein. 表位 Mature Form 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Cat. # AB15138 recognizes the mature form of Nogo Receptor. 品种反应性 HumanMouseRat Species Reactivity Note Mouse and rat. May react with human and primate based on sequence homology. Reactivity with other species has not been determined. 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_022982
纯化方法 Protein A purfied UniProt编号 - Q99PI8
产品使用声明 质量保证 Routinely tested on mouse cerebellum lysate.
Lot Specific Tested Application 1: Western Blot
使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt. 包装信息 数量 100 µg
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