merck millipore,默克密理愽
  • merck millipore,默克密理博,178501,APT1 Inhibitor, palmostatin B - Calbiochem

  • merck millipore,默克密理博,178501,APT1 Inhibitor, palmostatin B - Calbiochem

    产品名称：APT1 Inhibitor, palmostatin B - Calbiochem
    产品型号：178501
    The APT1 Inhibitor, palmostatin B controls the biological activity of APT1.

    merck millipore,默克密理博,178501,APT1 Inhibitor, palmostatin B - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,178501,APT1 Inhibitor, palmostatin B - Calbiochem

    重要规格表

    经验配方
    C₂₃H₃₆O₄
    描述
    概述 A cell-permeable, beta-lactone acyl protein thioesterase 1 (APT1) inhibitor (IC50 = 0.67 µM, in an enzymatic assay) that is shown to specifically block Ras depalmitoylation, without affecting Ras acylation, in MDCK cells, both in vitro and in vivo. It induces a marked redistribution of NRas to endomembranes (1 µM) without notable cytotoxicity, and is shown to elicit a loss of the precise steady-state localization of palmitoylated Ras proteins in the same cell line. At 50 µM, this inhibitor displays a partial phenotypic reversion in oncogenic HRasG12V-transformed fibroblasts. Furthermore, it demonstrates selectivity for APT1 over phospholipase A1, A2, Cβ and D. It's inhibitory effect is demonstrated to be consistent with that of APT1 downregulation by siRNA. Also available as a 50 mM solution in DMSO (Cat. No. 508738).
    产品目录编号 178501
    品牌系列 Calbiochem®
    同义词 APT1 Inhibitor
    参考
    参考 Dekker, F. and Hedberg, C. 2011. Bioorg. Med. Chem. Lett. 19, 1376.
    Dekker, F., et al. 2010. Nat. Chem. Biol. 6, 449.
    产品信息
    形式 Off-white solid
    Hill配方 C₂₃H₃₆O₄
    化学配方 C₂₃H₃₆O₄
    Molar Mass 376.53
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,178501,APT1 Inhibitor, palmostatin B - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,MABE64,Anti-TDRD7 Antibody, clone E6
下一件merck millipore产品：merck millipore,默克密理博,06-222,Anti-PP2A Antibody, C subunit


相关产品

merck millipore,默克密理博,ST1568,Anti-DEFB4 Mouse mAb (4C4) merck millipore,默克密理博,ST1568,Anti-DEFB4 Mouse mAb (4C4)

merck millipore,默克密理博,MABS465,Anti-Nampt, clone 14A.5 Antibody merck millipore,默克密理博,MABS465,Anti-Nampt, clone 14A.5 Antibody

merck millipore,默克密理博,7370-OP,OmniPur Riboflavin - CAS 83-88-5 - Calbiochem merck millipore,默克密理博,7370-OP,OmniPur Riboflavin - CAS 83-88-5 - Calbiochem

merck millipore,默克密理博,152226,AEC Substrate Buffer merck millipore,默克密理博,152226,AEC Substrate Buffer

merck millipore,默克密理博,MABE64,Anti-TDRD7 Antibody, clone E6 merck millipore,默克密理博,MABE64,Anti-TDRD7 Antibody, clone E6

merck millipore,默克密理博,06-222,Anti-PP2A Antibody, C subunit merck millipore,默克密理博,06-222,Anti-PP2A Antibody, C subunit

merck millipore,默克密理博,GF003,Fibroblast Growth Factor basic Protein, Human recombinant merck millipore,默克密理博,GF003,Fibroblast Growth Factor basic Protein, Human recombinant

merck millipore,默克密理博,MABT171,Anti-MMP-9 (Active) Antibody, clone 4A3 merck millipore,默克密理博,MABT171,Anti-MMP-9 (Active) Antibody, clone 4A3

merck millipore,默克密理博,181315,ARE Activator, BTZO-1 - Calbiochem merck millipore,默克密理博,181315,ARE Activator, BTZO-1 - Calbiochem

merck millipore,默克密理博,14-805M,Met (Y1248C) Protein, active, 250 µg merck millipore,默克密理博,14-805M,Met (Y1248C) Protein, active, 250 µg


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部