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merck millipore,默克密理博,MABT157,Anti-Parvin alpha Antibody, clone 7E2.1
产品名称：Anti-Parvin alpha Antibody, clone 7E2.1
产品型号：MABT157
This Anti-Parvin alpha Antibody, clone 7E2.1 is validated for use in western blotting & IHC (Paraffin) for the detection of Parvin alpha.
merck millipore,默克密理博,MABT157,Anti-Parvin alpha Antibody, clone 7E2.1
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB M Purified Monoclonal Antibody 描述 产品目录编号 MABT157 描述 Anti-Parvin alpha Antibody, clone 7E2.1 Alternate Names - Matrix-remodeling-associated protein 2
- Alpha-parvin
- α-Parvin
- a-Parvin
- topaxin
- CH-ILKBP
- Calponin-like integrin-linked kinase-binding protein
背景信息 The protein named α-Parvin or Parvin, or Actopaxin, or Calponin-like integrin-linked kinase-binding protein (CH-ILKBP), or Matrix-remodeling-associated protein 2 (MXRA2), and encoded by the gene PARVA/MXRA2, is a critical adhesion coupling protein involved in many systems including sarcomere organization, smooth muscle contraction, cardiovascular development, angiogenesis, actin cytoskeleton organization and the establishment of cell polarity, adhesion, spreading and migration. α-Parvin is required for the adhesion of smooth muscle cell to endothelial cells during blood vessel development and for the formation of lamellipodia and ciliogenesis. α-Parvin is localized to the cell junction and focal adhesions. The protein is peripheral membrane protein located on the cytoplasmic side of the cell membranes and interacts with the cytoskeleton in the cytoplasm. In muscle cells it is associated with the Z line of the sarcomere. α-Parvin is expressed many tissues including muscle, kidney and liver. 产品信息 格式 Purified 演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 This Anti-Parvin alpha Antibody, clone 7E2.1 is validated for use in western blotting & IHC (Paraffin) for the detection of Parvin alpha. 主要应用 - Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:2,000 dilution and a 1:50 dilution from a representative lot detected Parvin alpha in human kidney and skeletal muscle tissues, respectively. 生物信息 免疫原品种 GST-tagged recombinant protein corresponding to human Parvin. 克隆 7E2.1 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG1κ 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_060692
基因符号 - MXRA2
- PARVA
纯化方法 Protein G purified UniProt编号 - Q9NVD7
产品使用声明 质量保证 Evaluated by Western Blotting in human heart tissue.
Western Blotting Analysis: 0.2 µg/mL of this antibody detected Parvin alpha in 200 µg of human heart tissue.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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