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经验配方 CAS号 C₁₂H₁₅N₅O₅ 18417-89-5 描述 概述 A cytotoxic purine nucleoside active against human cytomegalovirus (HCMV). A cell-permeable, reversible, selective, and potent protein kinase C (PKC) inhibitor (IC50 = 10 µM). The inhibition is competitive with respect to ATP and non-competitive with respect to histone and lipid cofactors. 产品目录编号 559307 品牌系列 Calbiochem®
同义词 7-Deaza-7-carbamoyladenosine, NSC-65346 参考 参考 Greene, N.M., et al. 1995. J. Biol. Chem. 270, 6710.
Osada, H., et al. 1989. J. Antibiot. 42, 402.
Loomis, C.R. and Bell, R.M. 1988. J. Biol. Chem. 263, 1682.
Turk, S.R., et al. 1987. Antimicrob. Agents Chemother. 31, 544.产品信息 CAS号 18417-89-5 具有ATP竞争性 N 形式 White solid Hill配方 C₁₂H₁₅N₅O₅ 化学配方 C₁₂H₁₅N₅O₅ Molar Mass 309.3 可逆 N 结构配方图像 生物信息 主靶 PKC 主靶IC50 10 µM against PKC 纯度 ≥98% by HPLC 理化信息 细胞可渗透 Y 溶解度 0.1 M KOH GHS安全信息 RTECS UY9355000 安全信息 R相 R: 26/27/28
Very toxic by inhalation, in contact with skin and if swallowed.S相 S: 36/37/39-45
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).储存和货运信息 货运代码 Ambient Temperature Only
毒性 Highly Toxic
有害材料注意事项： Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
储存 +2°C to +8°C
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
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下一件merck millipore产品：merck millipore,默克密理博,475859,Mitochondrial Fusion Promoter, M1 - CAS 219315-22-7 - Calbiochem
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