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品种反应性 主要应用 宿主 格式 抗体类型 M WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABN526 描述 Anti-FAH Antibody Alternate Names - FAH
- Fumarylacetoacetase
- FAA
- Beta-diketonase
- Fumarylacetoacetate hydrolase
背景信息 The protein currently named Fumarylacetoacetase or alternatively Beta-diketonase, or Fumarylacetoacetate hydrolase, and encoded by the human gene named FAH, is an enzyme involved in amino acid catabolism. FAH is the last in a series of five enzymes needed to break down the amino acid tyrosine, a protein building block found in many foods. More specifically, FAH converts a tyrosine byproduct called fumarylacetoacetate into smaller molecules that are either excreted by the kidneys or used in reactions that produce energy. FAH also breaks down phenylalanine into acetoacetate and fumarate. FAH is expressed in most tissues but highest expression is in the liver and kidney. The disease tyrosinemia is associated with defective FAH and toxic tyrosine intermediates (fumarylacetoacetate). Defects in FAH are associated with liver disease and liver cancer. EMD-Millipore Anti-FAH rabbit polyclonal antibody has been tested in western blots on mouse liver extracts. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide and 50% glycerol. 应用 应用 Detect Fumarylacetoacetase using this rabbit polyclonal antibody, Anti-FAH Antibody validated for use in western blotting. 主要应用 - Western Blotting
生物信息 免疫原品种 GST-tagged fusion protein corresponding to human FAH. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Mouse 抗体类型 Polyclonal Antibody 基因符号 - FAH
纯化方法 Antigen Affinity purified UniProt编号 - P16930
产品使用声明 质量保证 Evaluated by Western Blotting in mouse liver tissue lysate.
Western Blotting Analysis: A 1:500 dilution of this antibody detected FAH in mouse liver tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 150 µL
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