merck millipore,默克密理愽
  • merck millipore,默克密理博,04-811,Anti-phospho-eNOS/NOS III (Thr495) Antibody, rabbit monoclonal

  • merck millipore,默克密理博,04-811,Anti-phospho-eNOS/NOS III (Thr495) Antibody, rabbit monoclonal

    产品名称：Anti-phospho-eNOS/NOS III (Thr495) Antibody, rabbit monoclonal
    产品型号：04-811
    This Anti-phospho-eNOS/NOS III (Thr495) Antibody is validated for use in WB for the detection of phospho-eNOS/NOS III (Thr495).

    merck millipore,默克密理博,04-811,Anti-phospho-eNOS/NOS III (Thr495) Antibody, rabbit monoclonal

  • 产品介绍
  • merck millipore,默克密理博,04-811,Anti-phospho-eNOS/NOS III (Thr495) Antibody, rabbit monoclonal

    Replacement Information
    Replacement Information Cat. # 05-811. 05-811 will only be availabe on a custom basis.

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    BWBRbCulture SupernatantMonoclonal Antibody
    描述
    产品目录编号 04-811
    Replaces 05-811
    品牌系列 Upstate
    商名
    • Upstate
    描述 Anti-phospho-eNOS/NOS III (Thr495) Antibody, rabbit monoclonal
    概述 Note: ADMA (Catalog #19-169) and NMMA (Catalog #19-170) are inhibitors of NOS
    Alternate Names
    • nitric oxide synthase 3 (endothelial cell)
    • NOS III
    • endothelial nitric oxidase synthase
    • endothelial nitric oxide synthase
    产品信息
    格式 Culture Supernatant
    控制
    • Fetal bovine heart endothelial cell lysate
    演示 Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.
    应用
    应用 This Anti-phospho-eNOS/NOS III (Thr495) Antibody is validated for use in WB for the detection of phospho-eNOS/NOS III (Thr495).
    主要应用
    • Western Blotting
    应用说明 Western Blot Analysis:
    A 1:2,000-1:10,000 dilution of this lot detected phosphorylated eNOS/NOS III in fetal bovine heart endothelial cell lysate.
    生物信息
    免疫原品种 Peptide containing the sequence KK[pT]FK in which pT corresponds to phosphothreonine at residue 495 of human eNOS/NOS III
    宿主 Rabbit
    特异性 Recognizes phosphorylated eNOS/NOS III.
    同种型 IgG
    品种反应性 Bovine
    Species Reactivity Note Predicted cross-reactivity with human, rabbit, mouse and rat
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_000603
    基因符号
    • NOSIII
    • NOS3
    • cNOS
    • ECNOS
    • eNOS
    • EC-NOS
    修改
    • Phosphorylation
    UniProt编号
    • P29474
    UniProt汇总 FUNCTION: SwissProt: P29474 # Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. No mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.
    COFACTOR: Heme group. & Binds 1 FAD. & Binds 1 FMN. & Metrahydrobiopterin (BH4). May stabilize the dimeric form of the enzyme.
    SIZE: 1203 amino acids; 133289 Da
    SUBUNIT: Homodimer. Interacts with NOSIP and NOSTRIN.
    SUBCELLULAR LOCATION: Cell membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Note=Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle; which is favored by interaction with NOSIP and results in a reduced enzymatic activity.
    TISSUE SPECIFICITY: Platelets, placenta, liver and kidney.
    SIMILARITY: SwissProt: P29474 ## Belongs to the NOS family. & Contains 1 flavodoxin-like domain.
    产品使用声明
    质量保证 routinely evaluated by immunoblot on fetal bovine heart endothelial cell lysate
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,04-811,Anti-phospho-eNOS/NOS III (Thr495) Antibody, rabbit monoclonal

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