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merck millipore,默克密理博,MABT140,Anti-Claudin-4 Antibody, clone 10B4.3
产品名称：Anti-Claudin-4 Antibody, clone 10B4.3
产品型号：MABT140
Anti-Claudin-4 Antibody, clone 10B4.3 is an antibody against Claudin-4 for use in western blotting & IHC (Paraffin).
merck millipore,默克密理博,MABT140,Anti-Claudin-4 Antibody, clone 10B4.3
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB M Purified Monoclonal Antibody 描述 产品目录编号 MABT140 描述 Anti-Claudin-4 Antibody, clone 10B4.3 Alternate Names - Williams-Beuren syndrome chromosomal region 8 protein
- Claudin-4
- Clostridium perfringens enterotoxin receptor
- CPE-R
- CPE-receptor
背景信息 Claudin 4, also known as Clostridium perfringens enterotoxin receptor, or CPE-R, or CPE-receptor or Williams-Beuren syndrome chromosomal region 8 protein, and encoded by the gene CLDN4/CPER/CPETR1/WBSCR8, plays a critical role in tight junction specific obliteration of intercellular space. Claudin 4 directly interacts with several important tight junction associated proteins including ZO-1,2,3 and EPHA2 proteins, and through these interactions, Claudin 4 regulates tight junction formation. Claudin 4 is localized to cell junctions and membranes at tight junctions. Claudin 4 is expressed in most tissues particularly in intestine, liver, and pancreas. Defects in Claudin 4 may be associated with Williams Beuren syndrome genetic deletion syndrome. Claudin 4 is also over expressed in many cancers and thus is a target of anti-cancer research using C. perfringens enterotoxin. 产品信息 格式 Purified 演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-Claudin-4 Antibody, clone 10B4.3 is an antibody against Claudin-4 for use in western blotting & IHC (Paraffin). 主要应用 - Western Blotting
应用说明 Western Blotting Analysis: 2.0 µg/mL from a representative lot detected Claudin-4 in 10 µg of MCF-7 cell lysate.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Claudin-4 in human ileum and human tonsil tissue.生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Claudin-4. 表位 Cytoplasmic domain 克隆 10B4.3 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG1κ 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_001296
基因符号 - WBSCR8
- CLDN4
- CPER
- CPETR1
纯化方法 Protein G purified UniProt编号 - O14493
产品使用声明 质量保证 Evaluated by Western Blotting in HeLa cell lysate.
Western Blotting Analysis: 2.0 µg/mL of this antibody detected Claudin-4 in 10 µg of HeLa cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,14-429M,MEK1 Protein, active, 250 µg
下一件merck millipore产品：merck millipore,默克密理博,PIMP30R48,Millicell 悬挂式细胞培养皿, PET 5.0 µm
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